Pelretin

Synthetic retinoid

Pelretin
Names

IUPAC name 14a,14b-Didehydro-14b,20-metheno-14a,14b-dihomoretinoic acid
Systematic IUPAC name 4-[(1E,3E,5E)-4-Methyl-6-(2,6,6-trimethylcyclohex-1-en-1-yl)hexa-1,3,5-trien-1-yl]benzoic acid
Identifiers
CAS Number	91587-01-8
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL39861^Y
ChemSpider	4940263
KEGG	D05402^Y
PubChem CID	6435504
UNII	H9MC68UEZ9^Y
InChI InChI=1S/C23H28O2/c1-17(10-15-21-18(2)8-6-16-23(21,3)4)7-5-9-19-11-13-20(14-12-19)22(24)25/h5,7,9-15H,6,8,16H2,1-4H3,(H,24,25)/b9-5+,15-10+,17-7+ Key: YRNAHKPMDMVFMV-GMICYETFSA-N InChI=1/C23H28O2/c1-17(10-15-21-18(2)8-6-16-23(21,3)4)7-5-9-19-11-13-20(14-12-19)22(24)25/h5,7,9-15H,6,8,16H2,1-4H3,(H,24,25)/b9-5+,15-10+,17-7+ Key: YRNAHKPMDMVFMV-GMICYETFBM
SMILES CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/c2ccc(cc2)C(=O)O)/C
Properties
Chemical formula	C₂₃H₂₈O₂
Molar mass	336.475 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Chemical compound

Pelretin is a synthetic retinoid. It was tested in the 1980s on animals in the hopes that it could be used to eliminate wrinkles.^[1]

References

^ Recer, Paul (11 December 1989). "Is Vitamin A Cream a New Wrinkle in Skin Care, or Just Soft Soap?". Los Angeles Times. Retrieved 20 December 2014.

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Retinoid receptor modulators

RARTooltip Retinoic acid receptor

Agonists: 9CDHRA
9-cis-Retinoic acid (alitretinoin)
AC-261066
AC-55649
Acitretin
Adapalene
all-trans-Retinoic acid (tretinoin)
AM-580
BMS-493
BMS-753
BMS-961
CD-1530
CD-2314
CD-437
Ch-55
EC 23
Etretinate
Fenretinide
Isotretinoin
Palovarotene
Retinoic acid
Retinol (vitamin A)
Tamibarotene
Tazarotene
Tazarotenic acid
Trifarotene
TTNPB

Antagonists: BMS-195614
BMS-493
CD-2665
ER-50891
LE-135
MM-11253

Retinoic acid metabolism inhibitors: Liarozole

RXRTooltip Retinoid X receptor

Agonists: 9CDHRA
9-cis-Retinoic acid (alitretinoin)
all-trans-Retinoic acid (tretinoin)
Bexarotene
CD 3254
Docosahexaenoic acid
Fluorobexarotene
Isotretinoin
LG-100268
LG-101506
LG-100754
Retinoic acid
Retinol (vitamin A)
SR-11237

Antagonists: HX-531
HX-630
LG-100754
PA-452
UVI-3003
HX-603
LE135 (RAR beta selective)
LE-540
CD3254
PA-451
PA-452
Rhein
HX-711
6-(N-ethyl-N-(5-isobutoxy-4-isopropyl-2-(E)-styrylphenyl)amino)nicotinic acid

See also: Receptor/signaling modulators

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