Pentifylline

Chemical compound

C04AD01 (WHO)

Identifiers

IUPAC name

1-Hexyl-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione

CAS Number

1028-33-7^Y

PubChem CID

70569

ChemSpider

63738^N

UNII

MBM1C4K26S

KEGG

D07174^Y

CompTox Dashboard (EPA)

DTXSID2057609

ECHA InfoCard100.012.584

Chemical and physical dataFormulaC₁₃H₂₀N₄O₂Molar mass264.329 g·mol⁻¹3D model (JSmol)

Interactive image

SMILES

CCCCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C

InChI

InChI=1S/C13H20N4O2/c1-4-5-6-7-8-17-12(18)10-11(14-9-15(10)2)16(3)13(17)19/h9H,4-8H2,1-3H3^N
Key:MRWQRJMESRRJJB-UHFFFAOYSA-N^N

^NY (what is this?) (verify)

Pentifylline (marketed as Cosaldon) is a vasodilator.^[1]

References

^ Bath PM, Bath-Hextall FJ (2004). "Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke". The Cochrane Database of Systematic Reviews (3): CD000162. doi:10.1002/14651858.CD000162.pub2. PMID 15266424.

Peripheral vasodilators (C04)

Phenylethanolamine derivatives

Isoxsuprine
Buphenine
Bamethan

Alpha blockers

Non-selective
Selective α₁-blockers
- Alfuzosin
- Doxazosin
- Prazosin
- Silodosin
- Tamsulosin
- Terazosin

Niacin and derivatives

Purine derivatives

Ergot alkaloids

Other peripheral vasodilators

v t e Phosphodiesterase inhibitors
PDE1	MMPX SCH-51866 Vinpocetine
PDE2	BAY 60-7550 Carbazeran EHNA Oxindole PDP
PDE3	Adibendan Amrinone (inamrinone) Anagrelide Benafentrine Bucladesine Carbazeran Cilostamide Cilostazol Enoximone Imazodan KMUP-1 Meribendan Milrinone Olprinone Parogrelil Pimobendan Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine
PDE4	Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466 Cilomilast Cipamfylline Crisaborole Denbutylline Difamilast Drotaverine Etazolate Filaminast Glaucine HT-0712 ICI-63197 Indimilast Irsogladine Lavamilast Lirimilast Lotamilast Luteolin Mesembrenone Mesembrine Mesopram Oglemilast Piclamilast Pumafentrine Revamilast Ro 20-1724 Roflumilast Rolipram Ronomilast RPL-554 RS-25344 Tetomilast Tofimilast YM-976 Zardaverine
PDE5	Acetildenafil Aildenafil Avanafil Beminafil Benzamidenafil Dasantafil Icariin Gisadenafil Homosildenafil Lodenafil Mirodenafil MY-5445 Nitrosoprodenafil Norcarbodenafil SCH-51866 Sildenafil Sulfoaildenafil T-0156 Tadalafil Udenafil Vardenafil
PDE7	BRL-50481
PDE9	BAY 73-6691 PF-04447943 Paraxanthine
PDE10	Balipodect Mardepodect Papaverine TC-E 5005 Tofisopam
PDE11	BC11-38
Non-selective	Aminophylline Caffeine Choline theophyllinate CPX Dipyridamole Doxofylline Enprofylline Ibudilast IBMX Luteolin Pentoxifylline Propentofylline Theobromine Theophylline Zaprinast
Unsorted	Diazepam Diprophylline DPCPX Furafylline Lisofylline MDL-12330A Moxaverine Oxagrelate Pentifylline Proxyphylline Quercetin Satigrel Tolafentrine Trapidil
See also: Receptor/signaling modulators