Phenylpiperazine
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Preferred IUPAC name 1-Phenylpiperazine | |
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ChemSpider |
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ECHA InfoCard | 100.001.969 |
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InChI
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Properties | |
Chemical formula | C10H14N2 |
Molar mass | 162.23 g/mol |
Appearance | clear colourless to yellow liquid |
Density | 1.028g/cm3 |
Melting point | 18.8 °C (65.8 °F; 291.9 K) |
Boiling point | 287.2 °C (549.0 °F; 560.3 K) at 760mmHg |
Solubility in water | insoluble |
Hazards | |
Flash point | 138.3 °C (280.9 °F; 411.4 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references |
Chemical compound
1-Phenylpiperazine is a simple chemical compound featuring a phenyl group bound to a piperazine ring. The suffix ‘-piprazole’ is sometimes used in the names of drugs to indicate they belong to this class.[1]
1-Phenylpiperazine is toxic, its oral LD50 in rats is 210 mg/kg.[2]
List phenylpiperazine derivatives
- Alpertine [27076-46-6]
- BP 554 [82900-57-0]
- Butropipazone [2354-61-2]
- CAM89 alluded to here: WO 2018102233
- Centphenaquin [98459-16-6]
- Centpropazine [91315-34-3] [34675-77-9]
- Clodoxopone [71923-34-7]
- Dropropizine [17692-31-8]
- Etoperidone
- FAUC-299 [313972-96-2]
- FAUC-312 [562104-72-7]
- LASSBio-579 [591774-47-9]
- LASSBio-581 [591774-48-0]
- LASSBio-632
- LASSBio-680
- LASSBio-724
- LASSBio-729 [66307-58-2]
- LASSBio-730
- McN 261 [1044-59-3]
- Nefazodone
- Niaprazine
- Oxypertine
- PD-158771 [189152-50-9]
- PO-219
- Trazodone
- WIN 18,437 [4121-77-1]
See also
- Substituted piperazine
- Serotonin antagonist and reuptake inhibitor
- Benzylpiperazine
- Diphenylpiperazine
- Diphenylmethylpiperazine
- Pyridinylpiperazine
- Pyrimidinylpiperazine
References
External links
- Media related to Phenylpiperazine at Wikimedia Commons
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(no additional rings)
- 2C-B-PP
- 3,4-CFP
- Acaprazine
- Antrafenine
- Aripiprazole
- Batoprazine
- Bifeprunox
- BRL-15,572
- Ciprofloxacin
- CSP-2503
- Dapiprazole
- DCPP
- DMPP
- Diphenylpiperazine
- Dropropizine
- EGIS-12,233
- Elopiprazole
- Eltoprazine
- Enpiprazole
- Ensaculin
- Etoperidone
- Flesinoxan
- Fluanisone
- Flibanserin
- Fluprazine
- Itraconazole
- Ketoconazole
- Levodropropizine
- Lorpiprazole
- mCPP
- Mefway
- MeOPP
- Mepiprazole
- Naftopidil
- Naluzotan
- Naphthylpiperazine
- Nefazodone
- Niaprazine
- Oxypertine
- Pardoprunox
- pCPP
- pFPP
- Posaconazole
- S-14,506
- S-14,671
- S-15,535
- SB-258,585
- SB-271,046
- SB-357,134
- SB-399,885
- Sonepiprazole
- TFMPP
- Tolpiprazole
- Trazodone
- Urapidil
- Vesnarinone
- Vilazodone
- Vortioxetine
- WAY-100,135
- WAY-100,635
(benzhydrylalkylpiperazines)
- AD-1211
- Almitrine
- Amperozide
- BRL-15,572
- Buclizine
- BW373U86
- Cetirizine
- Chlorbenzoxamine
- Chlorcyclizine
- Cinnarizine
- Clocinizine
- Cyclizine
- DBL-583
- Diphenpipenol
- Diphenylmethylpiperazine
- Dotarizine
- DPI-221
- DPI-287
- DPI-3290
- GBR-12,783
- GBR-12,935
- GBR-13,069
- GBR-13,098
- GBR-13,119
- Hydroxyzine
- Lidoflazine
- Manidipine
- Meclozine
- MT-45
- Oxatomide
- SNC-80
- Vanoxerine
(piperazine attached via side chain)
- Amoxapine
- Clopenthixol
- Clorotepine
- Clozapine
- Cyanothepin
- Doclothepin
- Docloxythepin
- Flupentixol
- Fluphenazine
- Isofloxythepin
- Loxapine
- Meperathiepin
- Metitepine
- Octomethothepin
- Olanzapine
- Opipramol
- Oxyclothepin
- Oxyprothepin
- Peradithiepin
- Perathiepin
- Perazine
- Perphenazine
- Pirenzepine
- Prochlorperazine
- Thiethylperazine
- Thiothixene
- Trifluoperazine
- Trifluthepin
- Zuclopenthixol
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