Phlorofucofuroeckol A
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Preferred IUPAC name 4,9-Bis(3,5-dihydroxyphenoxy)[1]benzofuro[3,2-a]oxanthrene-1,3,6,10,12-pentol | |
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Properties | |
Chemical formula | C30H18O14 |
Molar mass | 602.45 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
Phlorofucofuroeckol A is a phlorotannin isolated from brown algae species such as Eisenia bicyclis (an edible seaweed called arame in Japan),[1] Ecklonia cava,[2] Ecklonia kurome[3] or Ecklonia stolonifera.[4]
The molecule possesses both the dibenzo-1,4-dioxin and dibenzofuran elements.[3]
References
- ^ Eom, Sung-Hwan; Lee, Sang-Hoon; Yoon, Na-Young; Jung, Won-Kyo; Jeon, You-Jin; Kim, Se-Kwon; Lee, Myung-Suk; Kim, Young-Mog (2012). "Α-Glucosidase- and α-amylase-inhibitory activities of phlorotannins from Eisenia bicyclis". Journal of the Science of Food and Agriculture. 92 (10): 2084–90. doi:10.1002/jsfa.5585. PMID 22271637.
- ^ Ahn, MJ; Yoon, KD; Min, SY; Lee, JS; Kim, JH; Kim, TG; Kim, SH; Kim, NG; Huh, H; Kim, J (2004). "Inhibition of HIV-1 reverse transcriptase and protease by phlorotannins from the brown alga Ecklonia cava". Biological & Pharmaceutical Bulletin. 27 (4): 544–7. doi:10.1248/bpb.27.544. PMID 15056863.
- ^ a b Fukuyama, Y; Kodama, M; Miura, I; Kinzyo, Z; Mori, H; Nakayama, Y; Takahashi, M (1990). "Anti-plasmin inhibitor. VI. Structure of phlorofucofuroeckol A, a novel phlorotannin with both dibenzo-1,4-dioxin and dibenzofuran elements, from Ecklonia kurome Okamura". Chemical & Pharmaceutical Bulletin. 38 (1): 133–5. doi:10.1248/cpb.38.133. PMID 2337936.
- ^ Kim, AR; Lee, MS; Shin, TS; Hua, H; Jang, BC; Choi, JS; Byun, DS; Utsuki, T; Ingram, D; Kim, HR (2011). "Phlorofucofuroeckol a inhibits the LPS-stimulated iNOS and COX-2 expressions in macrophages via inhibition of NF-κB, Akt, and p38 MAPK". Toxicology in Vitro. 25 (8): 1789–95. doi:10.1016/j.tiv.2011.09.012. PMID 21963823.
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Types of phlorotannins (tannins in brown algae)
- Difucol
- Trifucol
- Tetrafucol A
- Tetrafucol B
- cis-Pentafucol A
- Diphlorethol and diphlorethol A
- Triphloroethol A
- Tetraphlorethol A, B, C and E
- Pentaphlorethol-B
- Hexaphlorethol-A
- Fucophlorethol A and B
- Fucodiphlorethol A, D and G
- Fucotriphlorethol-B, G and H
- Fucotetraphlorethol-B, J and K
- Fucopentaphlorethol-E
- Bisfucotriphlorethol-A
- Bisfucotetraphlorethol-A
- Bisfucopentaphlorethol-A and B
- Bisfucoheptaphlorethol-A
- Difucophlorethol-A
- Difucofucotriphlorethol-A and B
- Difucofucotetraphlorethol-A
- Terfucopentaphlorethol-A
- Terfucohexaphlorethol-A and B
- Terfucoheptaphlorethol-A
- Bifuhalol
- Trifuhalol A
- Tetrafuhalol A
- Tetraisofuhalol
- Dieckol
- Eckol
- Eckstolonol
- Phlorofucofuroeckol A and B
- 2-Phloroeckol
- 3-Phloroeckol
- 6,6'-Bieckol
- 7-Phloroeckol
- 8,4"'-Dieckol
- 8,8′-Bieckol
Bromotriphlorethol A1
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