RWDD2B

Protein-coding gene in the species Homo sapiens
RWDD2B
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2DAX

Identifiers
AliasesRWDD2B, C21orf6, GL011, RWD domain containing 2B
External IDsOMIM: 617843; MGI: 1858215; HomoloGene: 9654; GeneCards: RWDD2B; OMA:RWDD2B - orthologs
Gene location (Human)
Chromosome 21 (human)
Chr.Chromosome 21 (human)[1]
Chromosome 21 (human)
Genomic location for RWDD2B
Genomic location for RWDD2B
Band21q21.3Start29,004,384 bp[1]
End29,019,360 bp[1]
Gene location (Mouse)
Chromosome 16 (mouse)
Chr.Chromosome 16 (mouse)[2]
Chromosome 16 (mouse)
Genomic location for RWDD2B
Genomic location for RWDD2B
Band16|16 C3.3Start87,230,295 bp[2]
End87,237,461 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • Skeletal muscle tissue of biceps brachii

  • glutes

  • triceps brachii muscle

  • muscle of thigh

  • gastrocnemius muscle

  • vastus lateralis muscle

  • deltoid muscle

  • tendon of biceps brachii

  • right adrenal gland

  • right adrenal cortex
Top expressed in
  • otic vesicle

  • saccule

  • otic placode

  • intestinal villus

  • jejunum

  • duodenum

  • primary oocyte

  • proximal tubule

  • Paneth cell

  • ileum
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein binding
  • molecular function
Cellular component
  • cellular component
Biological process
  • biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

10069

53858

Ensembl

ENSG00000156253

ENSMUSG00000041079

UniProt

P57060

Q99M03

RefSeq (mRNA)

NM_016940
NM_001320724

NM_016924

RefSeq (protein)

NP_001307653
NP_058636

NP_058620

Location (UCSC)Chr 21: 29 – 29.02 MbChr 16: 87.23 – 87.24 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RWD domain-containing protein 2B is a protein that in humans is encoded by the RWDD2B gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000156253 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041079 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Orti R, Rachidi M, Vialard F, Toyama K, Lopes C, Taudien S, Rosenthal A, Yaspo ML, Sinet PM, Delabar JM (May 2000). "Characterization of a novel gene, C21orf6, mapping to a critical region of chromosome 21q22.1 involved in the monosomy 21 phenotype and of its murine ortholog, orf5". Genomics. 64 (2): 203–10. doi:10.1006/geno.1999.6109. PMID 10729227.
  6. ^ "Entrez Gene: C21orf6 chromosome 21 open reading frame 6".

Further reading

  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21". Nature. 405 (6784): 311–9. Bibcode:2000Natur.405..311H. doi:10.1038/35012518. PMID 10830953.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • v
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  • 2dax: Solution structure of the RWD domain of human protein C21orf6
    2dax: Solution structure of the RWD domain of human protein C21orf6


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