Rontalizumab

Chemical compound
 ☒NcheckY (what is this?)  (verify)

Rontalizumab is a humanized monoclonal antibody[1] being developed by Genentech.[2] As of November 2009[update], it is being investigated in a clinical trial for the treatment of systemic lupus erythematosus.[3][4]

References

  1. ^ WHO Drug Information
  2. ^ Genentech: Rontalizumab (rhuMAb IFN alpha)
  3. ^ Clinical trial number NCT00962832 for "A Study to Evaluate the Efficacy and Safety of Rontalizumab in Patients With Moderately to Severely Active Systemic Lupus Erythematosus (ROSE)" at ClinicalTrials.gov
  4. ^ Misra DP, Negi VS (March 2017). "Interferon targeted therapies in systemic lupus erythematosus". Mediterranean Journal of Rheumatology. 28 (1): 13–19. doi:10.31138/mjr.28.1.13. PMC 7045923. PMID 32185249.
  • v
  • t
  • e
Monoclonal antibodies for the immune system
Immune system
Human
Mouse
Chimeric
Humanized

Immune activation: Dostarlimab
Other: Ibalizumab

Chimeric + humanized
Interleukin
Human
Humanized
Veterinary
Inflammatory lesions
Mouse
  • v
  • t
  • e
Chemokine
  • See here instead.
CSF
Erythropoietin
G-CSF (CSF3)
GM-CSF (CSF2)
M-CSF (CSF1)
  • Kinase inhibitors: Agerafenib
SCF (c-Kit)
  • See here instead.
Thrombopoietin
Interferon
IFNAR (α/β, I)
IFNGR (γ, II)
IFNLR (λ, III)
  • See IL-28R (IFNLR) here instead.
Interleukin
  • See here instead.
TGFβ
  • See here instead.
TNF
  • See here instead.
Others
JAK
(inhibitors)
JAK1
JAK2
JAK3
TYK2
Others


Stub icon

This monoclonal antibody–related article is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e
Stub icon

This antineoplastic or immunomodulatory drug article is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e