SLC39A11

Protein-coding gene in the species Homo sapiens
SLC39A11
Identifiers
AliasesSLC39A11, C17orf26, ZIP11, solute carrier family 39 member 11, ZIP-11
External IDsOMIM: 616508 MGI: 1917056 HomoloGene: 12331 GeneCards: SLC39A11
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for SLC39A11
Genomic location for SLC39A11
Band17q24.3-q25.1Start72,645,949 bp[1]
End73,092,712 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for SLC39A11
Genomic location for SLC39A11
Band11|11 E2Start113,135,679 bp[2]
End113,540,905 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • bone marrow cells

  • pancreatic ductal cell

  • monocyte

  • rectum

  • liver

  • right lobe of liver

  • duodenum

  • islet of Langerhans

  • corpus callosum

  • left lobe of thyroid gland
Top expressed in
  • epithelium of stomach

  • pyloric antrum

  • parotid gland

  • mucous cell of stomach

  • submandibular gland

  • lacrimal gland

  • crypt of lieberkuhn of small intestine

  • duodenum

  • left colon

  • molar
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • metal ion transmembrane transporter activity
  • zinc ion transmembrane transporter activity
Cellular component
  • cytoplasm
  • integral component of membrane
  • plasma membrane
  • Golgi apparatus
  • nucleus
  • membrane
  • fungal-type vacuole membrane
Biological process
  • metal ion transport
  • zinc ion transport
  • ion transport
  • transmembrane transport
  • zinc ion transmembrane transport
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

201266

69806

Ensembl

ENSG00000133195
ENSG00000282291

ENSMUSG00000041654

UniProt

Q8N1S5

Q8BWY7

RefSeq (mRNA)

NM_001159770
NM_139177
NM_001352691
NM_001352692
NM_001352693

NM_001166503
NM_027216
NM_001362937
NM_001362938
NM_001362939

NM_001362940
NM_001362941
NM_001362942
NM_001362943
NM_001362944

RefSeq (protein)

NP_001153242
NP_631916
NP_001339620
NP_001339621
NP_001339622

NP_001159975
NP_081492
NP_001349866
NP_001349867
NP_001349868

NP_001349869
NP_001349870
NP_001349871
NP_001349872
NP_001349873

Location (UCSC)Chr 17: 72.65 – 73.09 MbChr 11: 113.14 – 113.54 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Solute carrier family 39 member 11 is a protein that in humans is encoded by the SLC39A11 gene. [5]

References

  1. ^ a b c ENSG00000282291 GRCh38: Ensembl release 89: ENSG00000133195, ENSG00000282291 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041654 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Solute carrier family 39 member 11". Retrieved 2017-10-11.

Further reading

  • Bagheri-Fam S, Ferraz C, Demaille J, Scherer G, Pfeifer D (2001). "Comparative genomics of the SOX9 region in human and Fugu rubripes: conservation of short regulatory sequence elements within large intergenic regions". Genomics. 78 (1–2): 73–82. doi:10.1006/geno.2001.6648. PMID 11707075.
  • Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
  • Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
  • Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S (2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study". Diabetes Care. 33 (10): 2250–3. doi:10.2337/dc10-0452. PMC 2945168. PMID 20628086.
  • Wu L, Chaffee KG, Parker AS, Sicotte H, Petersen GM (2015). "Zinc transporter genes and urological cancers: integrated analysis suggests a role for ZIP11 in bladder cancer". Tumour Biol. 36 (10): 7431–7. doi:10.1007/s13277-015-3459-2. PMC 4607554. PMID 25900876.


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