STK36

Protein-coding gene in the species Homo sapiens
STK36
Identifiers
AliasesSTK36, FU, serine/threonine kinase 36, CILD46
External IDsOMIM: 607652; MGI: 1920831; HomoloGene: 49432; GeneCards: STK36; OMA:STK36 - orthologs
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for STK36
Genomic location for STK36
Band2q35Start218,672,069 bp[1]
End218,702,716 bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for STK36
Genomic location for STK36
Band1|1 C4Start74,640,604 bp[2]
End74,676,053 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right uterine tube

  • anterior pituitary

  • left testis

  • right testis

  • right lobe of thyroid gland

  • right ovary

  • right adrenal cortex

  • left ovary

  • left lobe of thyroid gland

  • body of uterus
Top expressed in
  • gastrula

  • zygote

  • secondary oocyte

  • primary oocyte

  • spermatid

  • seminiferous tubule

  • Meckel's cartilage

  • occiput

  • occipital bone

  • humerus
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • nucleotide binding
  • protein binding
  • protein kinase activity
  • kinase activity
  • transferase activity
  • transcription factor binding
  • metal ion binding
  • protein serine/threonine kinase activity
  • ATP binding
Cellular component
  • nucleus
  • cytoplasm
  • cytosol
  • extracellular region
Biological process
  • phosphorylation
  • cell projection organization
  • regulation of DNA-binding transcription factor activity
  • multicellular organism development
  • epithelial cilium movement involved in extracellular fluid movement
  • brain development
  • positive regulation of smoothened signaling pathway
  • positive regulation of hh target transcription factor activity
  • protein phosphorylation
  • post-embryonic development
  • cilium assembly
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

27148

269209

Ensembl

ENSG00000163482

ENSMUSG00000033276

UniProt

Q9NRP7

Q69ZM6

RefSeq (mRNA)

NM_001243313
NM_015690
NM_001369423

NM_175031

RefSeq (protein)

NP_001230242
NP_056505
NP_001356352

NP_778196
NP_001391006
NP_001391007

Location (UCSC)Chr 2: 218.67 – 218.7 MbChr 1: 74.64 – 74.68 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Serine/threonine-protein kinase 36 is an enzyme that in humans is encoded by the STK36 gene.[5][6]


Interactions

STK36 has been shown to interact with GLI1.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163482 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033276 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Murone M, Luoh SM, Stone D, Li W, Gurney A, Armanini M, Grey C, Rosenthal A, de Sauvage FJ (Aug 2000). "Gli regulation by the opposing activities of fused and suppressor of fused". Nat Cell Biol. 2 (5): 310–2. doi:10.1038/35010610. PMID 10806483. S2CID 31424234.
  6. ^ "Entrez Gene: STK36 serine/threonine kinase 36, fused homolog (Drosophila)".

Further reading

  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Østerlund T, Everman DB, Betz RC, et al. (2005). "The FU gene and its possible protein isoforms". BMC Genomics. 5 (1): 49. doi:10.1186/1471-2164-5-49. PMC 512281. PMID 15268766.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Nakayama M, Kikuno R, Ohara O (2003). "Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs". Genome Res. 12 (11): 1773–84. doi:10.1101/gr.406902. PMC 187542. PMID 12421765.
  • Nagase T, Ishikawa K, Kikuno R, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (5): 337–45. doi:10.1093/dnares/6.5.337. PMID 10574462.
  • Gold MO, Yang X, Herrmann CH, Rice AP (1998). "PITALRE, the catalytic subunit of TAK, is required for human immunodeficiency virus Tat transactivation in vivo". J. Virol. 72 (5): 4448–53. doi:10.1128/JVI.72.5.4448-4453.1998. PMC 109679. PMID 9557739.


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