SoRI-9804
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Preferred IUPAC name N-(Diphenylmethyl)-2-phenylquinazolin-4-amine | |
Other names Benzhydryl-(2-phenyl-quinazolin-4-yl)-amine; 4-((Diphenylmethyl)amino)-2-phenylquinazoline | |
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Properties | |
Chemical formula | C27H21N3 |
Molar mass | 387.486 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
SoRI-9804 is a positive allosteric modulator of dopamine transporters. Unlike others in its series & traditional DRI ligands, it inhibits the release of dopamine in addition to inhibiting the reuptake of released dopamine back into the transporter.[1]
See also
- SoRI-20041
References
- ^ Rothman, Richard B.; Dersch, Christina M.; Ananthan, Subramaniam; Partilla, John S. (May 2009). "Studies of the biogenic amine transporters. 13. Identification of "agonist" and "antagonist" allosteric modulators of amphetamine-induced dopamine release". Journal of Pharmacology and Experimental Therapeutics. 329 (2): 718–28. doi:10.1124/jpet.108.149088. PMC 2672863. PMID 19244097.
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Dopamine receptor modulators
- See also: Receptor/signaling modulators
- Adrenergics
- Serotonergics
- Monoamine reuptake inhibitors
- Monoamine releasing agents
- Monoamine metabolism modulators
- Monoamine neurotoxins
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