Sodium channel opener
Medication group
A sodium channel opener is a type of drug which facilitates ion transmission through sodium channels.
Examples include toxins, such as aconitine, veratridine, batrachotoxin, robustoxin, palytoxin and ciguatoxins and insecticides (DDT and pyrethroids), which activate voltage-gated sodium channels (VGSCs), and solnatide (AP301), which activates the epithelial sodium channel (ENaC).[1]
See also
- Sodium channel blocker
References
- ^ Shabbir W, Tzotzos S, Bedak M, Aufy M, Willam A, Kraihammer M, Holzner A, Czikora I, Scherbaum-Hazemi P, Fischer H, Pietschmann H, Fischer B, Lucas R, Lemmens-Gruber R (2015). "Glycosylation-dependent activation of epithelial sodium channel by solnatide". Biochem. Pharmacol. 98 (4): 740–53. doi:10.1016/j.bcp.2015.08.003. PMID 26254591.
- v
- t
- e
Pharmacomodulation
- ♦ Enzyme: Inducer
- Inhibitor
- ♦ Receptor: Agonist
- Partial agonist
- Antagonist
- Inverse agonist
- Positive allosteric modulator (PAM)
- Negative allosteric modulator (NAM)
- ♦ Miscellaneous: Precursor
- Cofactor
| Enzyme | see Enzyme inhibition |
|---|---|
| Ion channel | See Ion channel modulators |
| Receptor & transporter | |
| Miscellaneous |
|
 | This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e
