Sophoradin
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Preferred IUPAC name 2′,4,4′-Trihydroxy-3,3′,5-tris(3-methylbut-2-en-1-yl)chalcone | |
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Chemical formula | C30H36O4 |
Molar mass | 460.614 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Chemical compound
Sophoradin is an isoprenyl chalconoid,[1] a type of polyphenolic compound, found in Sophora tonkinensis, an herb used in traditional Chinese medicine.
Sofalcone is an oral gastrointestinal medication and a synthetic analog of sophoradin.[2]
References
- ^ Synthesis of Isoprenyl Chalcone “Sophoradin” Isolated from Sophora subprostrata. Kazuaki Kyogoku, Katsuo Hatayama, Sadakazu Yokamori, Teruya Seki and Ichiro Tanaka, Agricultural and Biological Chemistry, Vol.39, No.1 (1975) pp.133-138
- ^ Konturek SJ, Mrzozowski T, Drozdowicz D, Pawlik W, Sendur R (August 1987). "Gastroprotective and ulcer healing effects of solon, a synthetic flavonoid derivative of sophoradin". Hepatogastroenterology. 34 (4): 164–70. PMID 3478294.
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Chalconoids and their glycosides
- Butein
- Isoliquiritigenin
- Methyl hydroxychalcone
- Okanin
- Licochalcone A
- Sophoradin (prenylated)
- Tephrospinosin (3′,5′-diisopentenyl-2′,4′-dihydroxychalcone) (prenylated)
- Xanthohumol (prenylated)
- Cardamomin
- Flavokawin B
- Okanin 3,4,3′,4′-tetramethyl ether
- Pashanone (2',6'-Dihydroxy-3',4'-dimethoxychalcone)
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