SP3 |
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Identifiers |
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Aliases | SP3, SPR2, Sp3 transcription factor |
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External IDs | OMIM: 601804; MGI: 1277166; HomoloGene: 7952; GeneCards: SP3; OMA:SP3 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 2 (human)[1] |
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| Band | 2q31.1 | Start | 173,880,850 bp[1] |
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End | 173,965,373 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 2 (mouse)[2] |
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| Band | 2|2 C3 | Start | 72,766,771 bp[2] |
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End | 72,810,790 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - hair follicle
- germinal epithelium
- sural nerve
- superficial temporal artery
- mucosa of paranasal sinus
- Achilles tendon
- buccal mucosa cell
- skin of hip
- palpebral conjunctiva
- ventricular zone
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| Top expressed in | - granulocyte
- genital tubercle
- left lung lobe
- migratory enteric neural crest cell
- hand
- thymus
- atrium
- dermis
- left colon
- ciliary body
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - DNA binding
- chromatin binding
- cis-regulatory region sequence-specific DNA binding
- metal ion binding
- DNA-binding transcription repressor activity, RNA polymerase II-specific
- protein binding
- nucleic acid binding
- DNA-binding transcription factor activity, RNA polymerase II-specific
- double-stranded DNA binding
- DNA-binding transcription factor activity
- RNA polymerase II transcription regulatory region sequence-specific DNA binding
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
| Cellular component | - PML body
- transcription repressor complex
- nucleus
- nucleoplasm
- protein-DNA complex
| Biological process | - megakaryocyte differentiation
- regulation of transcription, DNA-templated
- ossification
- lung development
- embryonic placenta development
- in utero embryonic development
- negative regulation of transcription by RNA polymerase II
- monocyte differentiation
- protein sumoylation
- transcription, DNA-templated
- embryonic skeletal system development
- positive regulation of transcription, DNA-templated
- embryonic process involved in female pregnancy
- T cell differentiation
- granulocyte differentiation
- embryonic camera-type eye morphogenesis
- trophectodermal cell differentiation
- enucleate erythrocyte differentiation
- erythrocyte differentiation
- definitive hemopoiesis
- liver development
- B cell differentiation
- negative regulation of transcription, DNA-templated
- positive regulation of transcription by RNA polymerase II
- natural killer cell differentiation
- regulation of transcription by RNA polymerase II
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_003111 NM_001017371 NM_001172712 |
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NM_001018042 NM_001098425 NM_011450 |
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RefSeq (protein) | |
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NP_001017371 NP_001166183 NP_003102 NP_003102.1 |
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Location (UCSC) | Chr 2: 173.88 – 173.97 Mb | Chr 2: 72.77 – 72.81 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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