Streptogramin
Class of natural cyclic peptide antibiotics produced by certain subspecies of Streptomyces
Streptogramins are a class of antibiotics.[1]
Streptogramins are effective in the treatment of vancomycin-resistant Staphylococcus aureus (VRSA) and vancomycin-resistant Enterococcus (VRE), two of the most rapidly growing strains of multidrug-resistant bacteria. They fall into two groups: streptogramin A and streptogramin B.[citation needed]
Members include:
- Quinupristin/dalfopristin
- Pristinamycin
- Virginiamycin
- NXL 103, an experimental streptogramin in clinical trials for the treatment of respiratory tract infections.[2]
References
- ^ University of Leeds: Antimicrobial Chemotherapy Archived 2007-04-28 at the Wayback Machine
- ^ Boucher, H. W.; Talbot, G. H.; Bradley, J. S.; Edwards, J. E.; Gilbert, D; Rice, L. B.; Scheld, M; Spellberg, B; Bartlett, J (2009). "Bad bugs, no drugs: No ESKAPE! An update from the Infectious Diseases Society of America". Clinical Infectious Diseases. 48 (1): 1–12. doi:10.1086/595011. PMID 19035777.
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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