Protein family
| G protein-coupled receptor 27 |
|---|
| Identifiers |
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| Symbol | GPR27 |
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| Alt. symbols | SREB1 |
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| NCBI gene | 2850 |
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| HGNC | 4482 |
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| OMIM | 605187 |
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| RefSeq | NM_018971 |
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| UniProt | Q9NS67 |
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| Other data |
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| Locus | Chr. 3 p21-p14 |
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| Search for |
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| Structures | Swiss-model |
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| Domains | InterPro |
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|
| G protein-coupled receptor 85 |
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| Identifiers |
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| Symbol | GPR85 |
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| Alt. symbols | SREB2 |
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| NCBI gene | 54329 |
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| HGNC | 4536 |
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| OMIM | 605188 |
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| RefSeq | NM_018970 |
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| UniProt | P60893 |
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| Other data |
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| Locus | Chr. 7 q31 |
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| Search for |
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| Structures | Swiss-model |
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| Domains | InterPro |
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|
| G protein-coupled receptor 173 |
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| Identifiers |
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| Symbol | GPR173 |
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| Alt. symbols | SREB3 |
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| NCBI gene | 54328 |
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| HGNC | 18186 |
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| OMIM | 300253 |
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| RefSeq | NM_018969 |
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| UniProt | Q9NS66 |
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| Other data |
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| Locus | Chr. X p11 |
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| Search for |
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| Structures | Swiss-model |
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| Domains | InterPro |
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|
The Super Conserved Receptor Expressed in Brain (SREB) family are a group of related G-protein coupled receptors.[1] Since no endogenous ligands have yet been identified for these receptors, they are classified as orphan receptors. Receptors within the group include SREB1 (GPR27), SREB2 (GPR85), and SREB3 (GPR173).[2]
References
- ^ Matsumoto M, Saito T, Takasaki J, Kamohara M, Sugimoto T, Kobayashi M, Tadokoro M, Matsumoto S, Ohishi T, Furuichi K (2000). "An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system". Biochem. Biophys. Res. Commun. 272 (2): 576–82. doi:10.1006/bbrc.2000.2829. PMID 10833454.
- ^ National Center for Biotechnology Information, [https://www.ncbi.nlm.nih.gov/Structure/cdd/cd15216 Conserved Protein Domain Family 7tmA_SREB1_GPR27], accessed 5 February 2022
External links
- IUPHAR GPCR Database - GPR27 (previously SREB1)
- IUPHAR GPCR Database - GPR85 (previously SREB2) Archived 2016-03-03 at the Wayback Machine
- IUPHAR GPCR Database - GPR173 (previously SREB3) Archived 2016-03-03 at the Wayback Machine
- GPR27+protein at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- GPR85+receptor at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
