TFAP2D

Mammalian protein found in Homo sapiens
TFAP2D
Identifiers
AliasesTFAP2D, TFAP2BL1, transcription factor AP-2 delta, AP-2delta
External IDsOMIM: 610161 MGI: 2153466 HomoloGene: 17700 GeneCards: TFAP2D
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for TFAP2D
Genomic location for TFAP2D
Band6p12.3Start50,713,526 bp[1]
End50,773,033 bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for TFAP2D
Genomic location for TFAP2D
Band1|1 A3Start19,173,246 bp[2]
End19,236,570 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • oocyte

  • secondary oocyte

  • ganglionic eminence

  • ventral tegmental area

  • amygdala

  • superior frontal gyrus

  • prefrontal cortex

  • dorsolateral prefrontal cortex

  • Brodmann area 9

  • pancreas
Top expressed in
  • urethra

  • female urethra

  • male urethra

  • inferior colliculus

  • ganglionic eminence

  • external carotid artery

  • superior frontal gyrus

  • temporal muscle

  • amygdala

  • digastric muscle
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • DNA-binding transcription factor activity
  • DNA binding
  • RNA polymerase II transcription regulatory region sequence-specific DNA binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • nucleus
  • transcription regulator complex
Biological process
  • negative regulation of neuron apoptotic process
  • positive regulation of transcription, DNA-templated
  • regulation of transcription, DNA-templated
  • regulation of cell population proliferation
  • inferior colliculus development
  • transcription, DNA-templated
  • positive regulation of transcription by RNA polymerase II
  • anatomical structure development
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

83741

226896

Ensembl

ENSG00000008197

ENSMUSG00000042596

UniProt

Q7Z6R9

Q91ZK0

RefSeq (mRNA)

NM_172238

NM_153154
NM_001379073
NM_001379074

RefSeq (protein)

NP_758438

NP_694794
NP_001366002
NP_001366003

Location (UCSC)Chr 6: 50.71 – 50.77 MbChr 1: 19.17 – 19.24 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transcription factor AP-2 delta (activating enhancer binding protein 2 delta), also known as TFAP2D, is a human gene. The protein encoded by this gene is a transcription factor.[5]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000008197 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042596 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Cheng C, Ying K, Xu M, Zhao W, Zhou Z, Huang Y, Wang W, Xu J, Zeng L, Xie Y, Mao Y (January 2002). "Cloning and characterization of a novel human transcription factor AP-2 beta like gene (TFAP2BL1)". Int. J. Biochem. Cell Biol. 34 (1): 78–86. doi:10.1016/S1357-2725(01)00098-X. PMID 11733187.

External links

  • v
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  • e
(1) Basic domains
(1.1) Basic leucine zipper (bZIP)
(1.2) Basic helix-loop-helix (bHLH)
Group A
Group B
Group C
bHLH-PAS
Group D
Group E
Group F
bHLH-COE
(1.3) bHLH-ZIP
(1.4) NF-1
(1.5) RF-X
(1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4)
subfamily 1
subfamily 2
subfamily 3
subfamily 4
subfamily 5
subfamily 6
subfamily 0
(2.2) Other Cys4
(2.3) Cys2His2
(2.4) Cys6
(2.5) Alternating composition
(2.6) WRKY
(3) Helix-turn-helix domains
(3.1) Homeodomain
Antennapedia
ANTP class
protoHOX
Hox-like
metaHOX
NK-like
other
(3.2) Paired box
(3.3) Fork head / winged helix
(3.4) Heat shock factors
(3.5) Tryptophan clusters
(3.6) TEA domain
  • transcriptional enhancer factor
(4) β-Scaffold factors with minor groove contacts
(4.1) Rel homology region
(4.2) STAT
(4.3) p53-like
(4.4) MADS box
(4.6) TATA-binding proteins
(4.7) High-mobility group
(4.9) Grainyhead
(4.10) Cold-shock domain
(4.11) Runt
(0) Other transcription factors
(0.2) HMGI(Y)
(0.3) Pocket domain
(0.5) AP-2/EREBP-related factors
(0.6) Miscellaneous
see also transcription factor/coregulator deficiencies


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