TTBK1 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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4BTJ, 4BTK, 4BTM, 4NFM, 4NFN |
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Identifiers |
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Aliases | TTBK1, BDTK, tau tubulin kinase 1 |
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External IDs | MGI: 2147036; HomoloGene: 50342; GeneCards: TTBK1; OMA:TTBK1 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 6 (human)[1] |
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| Band | 6p21.1 | Start | 43,243,481 bp[1] |
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End | 43,288,258 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 17 (mouse)[2] |
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| Band | 17|17 C | Start | 46,753,374 bp[2] |
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End | 46,798,601 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - lateral nuclear group of thalamus
- prefrontal cortex
- postcentral gyrus
- right frontal lobe
- right hemisphere of cerebellum
- superior frontal gyrus
- anterior cingulate cortex
- entorhinal cortex
- Brodmann area 9
- amygdala
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| Top expressed in | - superior frontal gyrus
- primary visual cortex
- seminiferous tubule
- dentate gyrus of hippocampal formation granule cell
- cerebellar cortex
- Rostral migratory stream
- primary motor cortex
- cingulate gyrus
- spermatid
- subiculum
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - transferase activity
- nucleotide binding
- protein kinase activity
- protein serine/threonine kinase activity
- ATP binding
- kinase activity
- tau protein binding
- tau-protein kinase activity
| Cellular component | - cytoplasm
- nucleus
- nucleoplasm
- cytosol
- microtubule associated complex
- neuronal cell body
- perinuclear region of cytoplasm
| Biological process | - protein phosphorylation
- peptidyl-serine phosphorylation
- substantia nigra development
- phosphorylation
- regulation of cell shape
- learning or memory
- positive regulation of gene expression
- negative regulation of gene expression
- peptidyl-threonine phosphorylation
- peptidyl-tyrosine phosphorylation
- negative regulation of protein binding
- positive regulation of protein polymerization
- positive regulation of astrocyte activation
- positive regulation of microglial cell activation
- positive regulation of cyclin-dependent protein kinase activity
- positive regulation of cysteine-type endopeptidase activity
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 6: 43.24 – 43.29 Mb | Chr 17: 46.75 – 46.8 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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