Teflurane
Chemical compound
- None
- 2-Bromo-1,1,1,2-tetrafluoroethane
- 124-72-1
- 31300
- 29040
- 6492U1O9V8
- DTXSID10861765
- Interactive image
- C(C(F)(F)F)(F)Br
InChI
- InChI=1S/C2HBrF4/c3-1(4)2(5,6)7/h1H
- Key:RZXZIZDRFQFCTA-UHFFFAOYSA-N
Teflurane (INN, USAN, code name Abbott 16900) is a halocarbon drug which was investigated as an inhalational anesthetic but was never marketed.[1][2] Its clinical development was terminated due to a high incidence of cardiac arrhythmias in patients, similarly to the cases of halopropane and norflurane.[3]
Chemistry
Teflurane is 2-bromo-1,1,1,2-tetrafluoroethane, a haloalkane. It is a gas at standard conditions.[4] The compound is chiral.
See also
References
- ^ Klein SL (1993). A glossary of anesthesia and related terminology. Springer-Verlag. ISBN 978-0-387-97831-4.
- ^ Artusio JF, Mazzia VD (1962). Practical anesthesiology. Mosby. ISBN 9780608393322.
- ^ Stanley TH, Petty WC (6 December 2012). Anesthesia, The Heart and the Vascular System: Annual Utah Postgraduate Course in Anesthesiology 1987. Springer Science & Business Media. pp. 185–. ISBN 978-94-009-3295-1.
- ^ "2-Bromo-1,1,1,2-tetrafluoroethane". Chem Spider.
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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