Testosterone undecylenate
Chemical compound
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| Trade names | Durasteron, Triolandren (mixtures) |
| Other names | TUe; Testosterone undecenoate; 17β-Hydroxyandrost-4-en-3-one 17β-(undec-10-enoate) |
| Routes of administration | Intramuscular injection |
| Drug class | Androgen; Anabolic steroid; Androgen ester |
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| ECHA InfoCard | 100.045.099  |
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| Formula | C30H46O3 |
| Molar mass | 454.695 g·mol−1 |
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Testosterone undecylenate (TUe) is an androgen/anabolic steroid medication and androgen ester which is no longer marketed.[1][2][3] It was a component of Durasteron and Triolandren, long-acting mixtures of testosterone esters in oil solution that were administered by intramuscular injection.[4][5][6][7]
See also
- Boldenone undecylenate
- Testosterone propionate/testosterone enanthate/testosterone undecylenate
- Testosterone propionate/testosterone valerate/testosterone undecylenate
- List of androgen esters § Testosterone esters
References
- ^ Shapiro S, Weinburg K, Freedman L (1956). "Notes - Long-Acting Androgens". The Journal of Organic Chemistry. 21 (11): 1300–1302. doi:10.1021/jo01117a602. ISSN 0022-3263.
- ^ Gould D, Finckenor L, Hershberg EB, Cassidy J, Perlman PL (1957). "Long-acting Testosterone Esters. Some Considerations on their Biological Utilization1". Journal of the American Chemical Society. 79 (16): 4472–4475. doi:10.1021/ja01573a061. ISSN 0002-7863.
- ^ US 2855341, Meier, R; Wettstein, A & Lang, E, "Testosterone compositions", published 1958-10-07, assigned to Ciba pharmaceutical Products, Inc.
- ^ Schuermann H, Doepfmer R (1960). Fertilitätsstörungen beim Manne. Springer-Verlag. pp. 260–. ISBN 978-3-642-94784-1.
- ^ Ufer J (1960). Hormontherapie in der Frauenheilkunde: Grundlagen und Praxis. Gruyter. p. 153. ISBN 9783111138770.
- ^ Aakvaag A, Vogt JH (March 1969). "Plasma testosterone values in different forms of testosterone treatment". Acta Endocrinologica. 60 (3): 537–542. doi:10.1530/acta.0.0600537. PMID 5395873.
Triolandren®, for intramuscular use, kindly supplied by Ciba, Basel, through Kobro 8c Co., Oslo, containing three different testosterone esters, in the following amounts of testosterone equivalents per ml oil: propionate 20 mg; valerate 80 mg; undecylenate 150 mg.
- ^ Zachmann M, Prader A (January 1970). "Anabolic and androgenic effect of testosterone in sexually immature boys and its dependency on growth hormone". The Journal of Clinical Endocrinology and Metabolism. 30 (1): 85–95. doi:10.1210/jcem-30-1-85. PMID 4311616.
Triolandren, CIBA; 250 mg of this preparation contains 20 mg of testosterone propionate, 80 mg of testosterone-n-valerianate, and 150 mg of testosterone undecylenate—250 mg thus contains 173.8 mg of testosterone; the remaining 76.2 mg consists of the ester components [...]
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
- See also
- Androgen receptor modulators
- Estrogens and antiestrogens
- Progestogens and antiprogestogens
- List of androgens/anabolic steroids
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