Traditional serrated adenoma

Traditional serrated adenomas
Traditional serrated adenoma with intermediate magnification, showing serrated crypts and cytologic atypia (H&E stain).
Specialty	Gastroenterology
Symptoms	Asymptomatic
Complications	Colorectal cancer
Usual onset	>50 years of age
Diagnostic method	Colonoscopy
Treatment	Polypectomy
Frequency	<1% of all colon polyps

Traditional serrated adenoma is a premalignant type of polyp found in the colon, often in the distal colon (sigmoid, rectum). Traditional serrated adenomas are a type of serrated polyp, and may occur sporadically or as a part of serrated polyposis syndrome. Traditional serrated adenomas are relatively rare, accounting for less than 1% of all colon polyps.^[1][2] Usually, traditional serrated adenomas are found in the distal colon and are usually less than 10 mm in size.^[1]

Histopathology

Traditional serrated adenomas are characterized by ectopic crypts, pseudostratification, and a villous pattern with stretched nuclei.^[3]

Epidemiology

Usually found in individuals over the age of 50 years, traditional serrated adenomas affect men and women equally.^[1] The overall prevalence of traditional serrated adenomas is less than 1% of the general population.^[3] Traditional serrated adenomas are the least common type of serrated polyps found in the colon, accounting for 5% of serrated colon polyps.^[4]

References