YTHDF1

Protein-coding gene in the species Homo sapiens
YTHDF1
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

4RCI, 4RCJ

Identifiers
AliasesYTHDF1, C20orf21, YTH N6-methyladenosine RNA binding protein 1, DF1
External IDsOMIM: 616529 MGI: 1917431 HomoloGene: 9844 GeneCards: YTHDF1
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for YTHDF1
Genomic location for YTHDF1
Band20q13.33Start63,195,429 bp[1]
End63,216,139 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for YTHDF1
Genomic location for YTHDF1
Band2|2 H4Start180,546,170 bp[2]
End180,562,742 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • middle temporal gyrus

  • internal globus pallidus

  • cerebellar vermis

  • tibia

  • pancreatic epithelial cell

  • tibialis anterior muscle

  • Brodmann area 23

  • thymus

  • nipple
Top expressed in
  • Paneth cell

  • primitive streak

  • condyle

  • fossa

  • renal corpuscle

  • internal carotid artery

  • motor neuron

  • medullary collecting duct

  • external carotid artery

  • facial motor nucleus
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • ribosome binding
  • N6-methyladenosine-containing RNA binding
  • RNA binding
  • protein binding
Cellular component
  • cytoplasm
Biological process
  • positive regulation of translational initiation
  • positive regulation of translation
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

54915

228994

Ensembl

ENSG00000149658

ENSMUSG00000038848

UniProt

Q9BYJ9

P59326

RefSeq (mRNA)

NM_017798

NM_173761

RefSeq (protein)

NP_060268

NP_776122

Location (UCSC)Chr 20: 63.2 – 63.22 MbChr 2: 180.55 – 180.56 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

YTH domain family, member 1 is a protein that in humans is encoded by the YTHDF1 gene. [5]

See also

N6-Methyladenosine

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000149658 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038848 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: YTH domain family, member 1". Retrieved 2013-08-14.

Further reading

External links

  • PDBe-KB provides an overview of all the structure information available in the PDB for Human YTH domain-containing family protein 1 (YTHDF1)


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