ZNF267

Protein-coding gene in the species Homo sapiens
ZNF267
Identifiers
AliasesZNF267, HZF2, zinc finger protein 267
External IDsOMIM: 604752 MGI: 1098769 HomoloGene: 117700 GeneCards: ZNF267
Gene location (Human)
Chromosome 16 (human)
Chr.Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for ZNF267
Genomic location for ZNF267
Band16p11.2Start31,873,807 bp[1]
End31,917,357 bp[1]
Gene location (Mouse)
Chromosome 3 (mouse)
Chr.Chromosome 3 (mouse)[2]
Chromosome 3 (mouse)
Genomic location for ZNF267
Genomic location for ZNF267
Band3 B|3 17.41 cMStart36,205,166 bp[2]
End36,224,491 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • oocyte

  • secondary oocyte

  • monocyte

  • Achilles tendon

  • amniotic fluid

  • blood

  • palpebral conjunctiva

  • bone marrow

  • appendix

  • germinal epithelium
Top expressed in
  • hand

  • superior cervical ganglion

  • supraoptic nucleus

  • ventromedial nucleus

  • mammillary body

  • lateral hypothalamus

  • aortic valve

  • medial ganglionic eminence

  • ascending aorta

  • otolith organ
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • DNA-binding transcription factor activity
  • DNA binding
  • metal ion binding
  • nucleic acid binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • intracellular anatomical structure
  • nucleus
Biological process
  • multicellular organism development
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

10308

241944

Ensembl

ENSG00000185947

ENSMUSG00000033883

UniProt

Q14586

n/a

RefSeq (mRNA)

NM_001265588
NM_003414

NM_001101478

RefSeq (protein)

NP_001252517
NP_003405

n/a

Location (UCSC)Chr 16: 31.87 – 31.92 MbChr 3: 36.21 – 36.22 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein 267 is a protein that in humans is encoded by the ZNF267 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000185947 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033883 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Abrink M, Aveskogh M, Hellman L (Mar 1995). "Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937". DNA Cell Biol. 14 (2): 125–36. doi:10.1089/dna.1995.14.125. PMID 7865130.
  6. ^ "Entrez Gene: ZNF267 zinc finger protein 267".

Further reading

  • Schäfer U, Schneider A, Neugebauer E (2001). "Identification of a nitric oxide-regulated zinc finger containing transcription factor using motif-directed differential display". Biochim. Biophys. Acta. 1494 (3): 269–76. doi:10.1016/s0167-4781(00)00249-9. PMID 11121585.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455. S2CID 7200157.
  • Hu K, Fink M, Froh M, et al. (2005). "Characterization of the human zinc finger protein 267 promoter: essential role of nuclear factor Y.". Biochim. Biophys. Acta. 1729 (1): 14–23. doi:10.1016/j.bbaexp.2005.03.001. PMID 15814297.
  • Schnabl B, Hu K, Mühlbauer M, et al. (2005). "Zinc finger protein 267 is up-regulated during the activation process of human hepatic stellate cells and functions as a negative transcriptional regulator of MMP-10". Biochem. Biophys. Res. Commun. 335 (1): 87–96. doi:10.1016/j.bbrc.2005.07.043. PMID 16054593.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

External links

  • v
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(1) Basic domains
(1.1) Basic leucine zipper (bZIP)
(1.2) Basic helix-loop-helix (bHLH)
Group A
Group B
Group C
bHLH-PAS
Group D
Group E
Group F
bHLH-COE
(1.3) bHLH-ZIP
(1.4) NF-1
(1.5) RF-X
(1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4)
subfamily 1
subfamily 2
subfamily 3
subfamily 4
subfamily 5
subfamily 6
subfamily 0
(2.2) Other Cys4
(2.3) Cys2His2
(2.4) Cys6
(2.5) Alternating composition
(2.6) WRKY
(3) Helix-turn-helix domains
(3.1) Homeodomain
Antennapedia
ANTP class
protoHOX
Hox-like
metaHOX
NK-like
other
(3.2) Paired box
(3.3) Fork head / winged helix
(3.4) Heat shock factors
(3.5) Tryptophan clusters
(3.6) TEA domain
  • transcriptional enhancer factor
(4) β-Scaffold factors with minor groove contacts
(4.1) Rel homology region
(4.2) STAT
(4.3) p53-like
(4.4) MADS box
(4.6) TATA-binding proteins
(4.7) High-mobility group
(4.9) Grainyhead
(4.10) Cold-shock domain
(4.11) Runt
(0) Other transcription factors
(0.2) HMGI(Y)
(0.3) Pocket domain
(0.5) AP-2/EREBP-related factors
(0.6) Miscellaneous
see also transcription factor/coregulator deficiencies


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