ZNF318

Protein-coding gene in humans
ZNF318
Identifiers
AliasesZNF318, TZF, ZFP318, HRIHFB2436, zinc finger protein 318
External IDsOMIM: 617512 MGI: 1889348 HomoloGene: 22808 GeneCards: ZNF318
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for ZNF318
Genomic location for ZNF318
Band6p21.1Start43,307,134 bp[1]
End43,369,647 bp[1]
Gene location (Mouse)
Chromosome 17 (mouse)
Chr.Chromosome 17 (mouse)[2]
Chromosome 17 (mouse)
Genomic location for ZNF318
Genomic location for ZNF318
Band17|17 CStart46,694,657 bp[2]
End46,731,846 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • lymph node

  • sural nerve

  • canal of the cervix

  • monocyte

  • sperm

  • right lobe of thyroid gland

  • left lobe of thyroid gland

  • ganglionic eminence

  • islet of Langerhans
Top expressed in
  • saccule

  • secondary oocyte

  • testicle

  • spermatocyte

  • seminiferous tubule

  • spleen

  • otic placode

  • spermatid

  • right ventricle

  • vas deferens
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • zinc ion binding
  • metal ion binding
  • nucleic acid binding
  • protein homodimerization activity
Cellular component
  • nucleus
  • nucleoplasm
  • cytosol
Biological process
  • regulation of transcription, DNA-templated
  • meiosis
  • transcription, DNA-templated
  • negative regulation of transcription, DNA-templated
  • positive regulation of transcription, DNA-templated
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

24149

57908

Ensembl

ENSG00000171467

ENSMUSG00000015597

UniProt

Q5VUA4

Q99PP2

RefSeq (mRNA)

NM_014345

NM_021346
NM_207671

RefSeq (protein)

NP_055160

NP_067321
NP_997554

Location (UCSC)Chr 6: 43.31 – 43.37 MbChr 17: 46.69 – 46.73 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein 318 is a protein that in humans is encoded by the ZNF318 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171467 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000015597 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Inoue A, Ishiji A, Kasagi S, Ishizuka M, Hirose S, Baba T, Hagiwara H (Jul 2000). "The transcript for a novel protein with a zinc finger motif is expressed at specific stages of mouse spermatogenesis". Biochemical and Biophysical Research Communications. 273 (2): 398–403. doi:10.1006/bbrc.2000.2953. PMID 10873617.
  6. ^ "Entrez Gene: ZNF318 zinc finger protein 318".

Further reading

  • Ueki N, Oda T, Kondo M, Yano K, Noguchi T, Muramatsu M (Dec 1998). "Selection system for genes encoding nuclear-targeted proteins". Nature Biotechnology. 16 (13): 1338–42. doi:10.1038/4315. PMID 9853615. S2CID 20001769.
  • Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (Aug 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Ishizuka M, Kawate H, Takayanagi R, Ohshima H, Tao RH, Hagiwara H (Jun 2005). "A zinc finger protein TZF is a novel corepressor of androgen receptor". Biochemical and Biophysical Research Communications. 331 (4): 1025–31. doi:10.1016/j.bbrc.2005.04.024. PMID 15882980.
  • Tao RH, Kawate H, Ohnaka K, Ishizuka M, Hagiwara H, Takayanagi R (Mar 2006). "Opposite effects of alternative TZF spliced variants on androgen receptor". Biochemical and Biophysical Research Communications. 341 (2): 515–21. doi:10.1016/j.bbrc.2005.12.213. PMID 16446156.
  • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


  • v
  • t
  • e
(1) Basic domains
(1.1) Basic leucine zipper (bZIP)
(1.2) Basic helix-loop-helix (bHLH)
Group A
Group B
Group C
bHLH-PAS
Group D
Group E
Group F
bHLH-COE
(1.3) bHLH-ZIP
(1.4) NF-1
(1.5) RF-X
(1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4)
subfamily 1
subfamily 2
subfamily 3
subfamily 4
subfamily 5
subfamily 6
subfamily 0
(2.2) Other Cys4
(2.3) Cys2His2
(2.4) Cys6
(2.5) Alternating composition
(2.6) WRKY
(3) Helix-turn-helix domains
(3.1) Homeodomain
Antennapedia
ANTP class
protoHOX
Hox-like
metaHOX
NK-like
other
(3.2) Paired box
(3.3) Fork head / winged helix
(3.4) Heat shock factors
(3.5) Tryptophan clusters
(3.6) TEA domain
  • transcriptional enhancer factor
(4) β-Scaffold factors with minor groove contacts
(4.1) Rel homology region
(4.2) STAT
(4.3) p53-like
(4.4) MADS box
(4.6) TATA-binding proteins
(4.7) High-mobility group
(4.9) Grainyhead
(4.10) Cold-shock domain
(4.11) Runt
(0) Other transcription factors
(0.2) HMGI(Y)
(0.3) Pocket domain
(0.5) AP-2/EREBP-related factors
(0.6) Miscellaneous
see also transcription factor/coregulator deficiencies


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