ZNF7

Protein-coding gene in the species Homo sapiens
ZNF7
Identifiers
AliasesZNF7, HF.16, KOX4, zf30, zinc finger protein 7
External IDsOMIM: 194531 MGI: 99208 HomoloGene: 20729 GeneCards: ZNF7
Gene location (Human)
Chromosome 8 (human)
Chr.Chromosome 8 (human)[1]
Chromosome 8 (human)
Genomic location for ZNF7
Genomic location for ZNF7
Band8q24.3Start144,827,518 bp[1]
End144,847,509 bp[1]
Gene location (Mouse)
Chromosome 15 (mouse)
Chr.Chromosome 15 (mouse)[2]
Chromosome 15 (mouse)
Genomic location for ZNF7
Genomic location for ZNF7
Band15 D3|15 36.28 cMStart76,763,459 bp[2]
End76,776,595 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • gastrocnemius muscle

  • right lobe of thyroid gland

  • left uterine tube

  • tibial nerve

  • skin of abdomen

  • left lobe of thyroid gland

  • canal of the cervix

  • body of pancreas

  • gastric mucosa

  • minor salivary glands
Top expressed in
  • outer renal medulla

  • inner renal medulla

  • connecting tubule

  • medullary collecting duct

  • cortical collecting duct

  • primitive streak

  • inner stripe of outer renal medulla

  • thyroid gland

  • cervix

  • pharynx
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • DNA-binding transcription factor activity
  • DNA binding
  • metal ion binding
  • nucleic acid binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • intracellular anatomical structure
  • nucleus
Biological process
  • multicellular organism development
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

7553

223669

Ensembl

ENSG00000147789

ENSMUSG00000033669

UniProt

P17097

Q3TFZ4

RefSeq (mRNA)
NM_001282795
NM_001282796
NM_001282797
NM_003416
NM_001330623

NM_001349805
NM_001349806
NM_001349807
NM_001349808
NM_001349809

NM_145916
NM_001358816
NM_001358817
NM_001358818

RefSeq (protein)
NP_001269724
NP_001269725
NP_001269726
NP_001317552
NP_003407

NP_001336734
NP_001336735
NP_001336736
NP_001336737
NP_001336738

NP_666021
NP_001345745
NP_001345746
NP_001345747

Location (UCSC)Chr 8: 144.83 – 144.85 MbChr 15: 76.76 – 76.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein 7 is a protein that in humans is encoded by the ZNF7 gene.[5][6][7]


Interactions

ZNF7 has been shown to interact with RPL7.[8]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000147789 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033669 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lania L, Donti E, Pannuti A, Pascucci A, Pengue G, Feliciello I, La Mantia G, Lanfrancone L, Pelicci PG (April 1990). "cDNA isolation, expression analysis, and chromosomal localization of two human zinc finger genes". Genomics. 6 (2): 333–40. doi:10.1016/0888-7543(90)90574-E. PMID 2106481.
  6. ^ Bray P, Lichter P, Thiesen HJ, Ward DC, Dawid IB (December 1991). "Characterization and mapping of human genes encoding zinc finger proteins". Proc Natl Acad Sci U S A. 88 (21): 9563–7. Bibcode:1991PNAS...88.9563B. doi:10.1073/pnas.88.21.9563. PMC 52758. PMID 1946370.
  7. ^ "Entrez Gene: ZNF7 zinc finger protein 7".
  8. ^ Witte, S; Krawinkel U (August 1997). "Specific interactions of the autoantigen L7 with multi-zinc finger protein ZNF7 and ribosomal protein S7". J. Biol. Chem. 272 (35). UNITED STATES: 22243–7. doi:10.1074/jbc.272.35.22243. ISSN 0021-9258. PMID 9268371.

Further reading

  • Thiesen HJ (1991). "Multiple genes encoding zinc finger domains are expressed in human T cells". New Biol. 2 (4): 363–74. PMID 2288909.
  • Fukunaga R, Hunter T (1997). "MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates". EMBO J. 16 (8): 1921–33. doi:10.1093/emboj/16.8.1921. PMC 1169795. PMID 9155018.
  • Witte S, Krawinkel U (1997). "Specific interactions of the autoantigen L7 with multi-zinc finger protein ZNF7 and ribosomal protein S7". J. Biol. Chem. 272 (35): 22243–7. doi:10.1074/jbc.272.35.22243. PMID 9268371.
  • Petroni D, Bartolini E, Chiaramonte R, et al. (1999). "Computer sequence analysis of human highly conserved zinc finger modules". DNA Seq. 9 (3): 163–9. doi:10.3109/10425179809072191. PMID 10520746.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

  • v
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  • e
(1) Basic domains
(1.1) Basic leucine zipper (bZIP)
(1.2) Basic helix-loop-helix (bHLH)
Group A
Group B
Group C
bHLH-PAS
Group D
Group E
Group F
bHLH-COE
(1.3) bHLH-ZIP
(1.4) NF-1
(1.5) RF-X
(1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4)
subfamily 1
subfamily 2
subfamily 3
subfamily 4
subfamily 5
subfamily 6
subfamily 0
(2.2) Other Cys4
(2.3) Cys2His2
(2.4) Cys6
(2.5) Alternating composition
(2.6) WRKY
(3) Helix-turn-helix domains
(3.1) Homeodomain
Antennapedia
ANTP class
protoHOX
Hox-like
metaHOX
NK-like
other
(3.2) Paired box
(3.3) Fork head / winged helix
(3.4) Heat shock factors
(3.5) Tryptophan clusters
(3.6) TEA domain
  • transcriptional enhancer factor
(4) β-Scaffold factors with minor groove contacts
(4.1) Rel homology region
(4.2) STAT
(4.3) p53-like
(4.4) MADS box
(4.6) TATA-binding proteins
(4.7) High-mobility group
(4.9) Grainyhead
(4.10) Cold-shock domain
(4.11) Runt
(0) Other transcription factors
(0.2) HMGI(Y)
(0.3) Pocket domain
(0.5) AP-2/EREBP-related factors
(0.6) Miscellaneous
see also transcription factor/coregulator deficiencies


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