Zaltoprofen
COX-2 selective NSAID medication
- US: Not FDA approved
- Japan: Rx-only
- 2-(6-Oxo-5H-benzo[b][1]benzothiepin-3-yl)propanoic acid
- 74711-43-6
- 5720
- DB06737
- H8635NG3PY
- DTXSID0049076
- Interactive image
- CC(C1=CC2=C(C=C1)SC3=CC=CC=C3C(=O)C2)C(=O)O
Zaltoprofen (JAN; trade name Soleton) is a nonsteroidal anti-inflammatory drug (NSAID) used as an analgesic, antipyretic, and anti-inflammatory agent.[1] It is a selective COX-2 inhibitor and also inhibits bradykinin-induced pain responses without blocking bradykinin receptors.[2]
It was approved for use in Japan in 1993.[3]
References
- ^ "Zaltoprofen". drugs.com.
- ^ Hirate K, Uchida A, Ogawa Y, Arai T, Yoda K (April 2006). "Zaltoprofen, a non-steroidal anti-inflammatory drug, inhibits bradykinin-induced pain responses without blocking bradykinin receptors". Neuroscience Research. 54 (4): 288–94. doi:10.1016/j.neures.2005.12.016. PMID 16473424. S2CID 27367042.
- ^ "Zaltoprofen Launched in Japan". thepharmaletter.com. September 20, 1993.
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