Chorionic gonadotropin alpha

CGA
Struktur yang tersedia PDB Pencarian Ortolog: PDBe RCSB Daftar kode id PDB 1DZ7, 1E9J, 1FL7, 1HCN, 1HD4, 1HRP, 1QFW, 1XWD, 4AY9, 4MQW
Pengidentifikasi
Alias	CGA, CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA, Chorionic gonadotropin alpha, glycoprotein hormones, alpha polypeptide, Alpha subunit of glycoprotein hormones, GPA1
ID eksternal	OMIM: 118850 MGI: 88390 HomoloGene: 587 GeneCards: CGA
Pola ekspresi RNA Referensi data ekspresi selengkapnya
Ontologi gen Fungsi molekuler • GO:0001948, GO:0016582 Ikatan protein plasma • hormone activity • follicle-stimulating hormone activity Komponen seluler • Golgi lumen • extracellular region • extracellular space • follicle-stimulating hormone complex Proses biologis • cell-cell signaling • peptide hormone processing • positive regulation of cell population proliferation • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • GO:0072468 signal transduction • positive regulation of cell migration • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • regulation of signaling receptor activity • G protein-coupled receptor signaling pathway • positive regulation of steroid biosynthetic process • thyroid hormone generation Sumber:Amigo / QuickGO
Ortolog
Spesies	Manusia	Tikus
Entrez	1081	12640
Ensembl	ENSG00000135346	ENSMUSG00000028298
UniProt	P01215	P01216
RefSeq (mRNA)	NM_001252383 NM_000735	NM_009889
RefSeq (protein)	NP_000726 NP_001239312	NP_034019
Lokasi (UCSC)	n/a	n/a
Pencarian PubMed	[1]	[2]
Wikidata
Lihat/Sunting Manusia Lihat/Sunting Tikus

CGA adalah nama berkas gen pada kromosom 6 lokasi 6q12-q21.^[3]

Empat hormon glikoprotein yakni gonadotropin, lutropin, FSH, TSH merupakan protein dimer yang terdiri dari sub-unit alfa dan beta. CGA merupakan berkas gen yang mengekspresikan protein sub-unit alfa yang identik untuk keempat hormon tersebut, sedangkan sub-unit beta diekspresikan oleh berkas gen yang berlainan.

Rujukan