SOX2 |
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사용 가능한 구조 |
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PDB | 동원체 검색: PDBe RCSB |
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식별자 |
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다른 이름 | SOX2, ANOP3, MCOPS3, SRY-box 2, Sox2, SRY-box transcription factor 2 |
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외부 ID | OMIM: 184429 MGI: 98364 HomoloGene: 68298 GeneCards: SOX2 |
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유전자 위치 (쥐) |
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| 염색체 | 3번 염색체 (쥐)[2] |
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| 자리 | 3 A3|3 16.93 cM | 시작 | 34,704,554 bp[2] |
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끝 | 34,706,610 bp[2] |
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RNA 발현 패턴 |
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Bgee | 인간 | 쥐(동원체) |
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최상위 발현 | - ventricular zone
- bronchial epithelial cell
- ganglionic eminence
- external globus pallidus
- pars reticulata
- dorsal motor nucleus of vagus nerve
- 배쪽 피개부
- superior vestibular nucleus
- oral cavity
- subthalamic nucleus
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| 최상위 발현 | - medial ganglionic eminence
- tooth germ
- Enamel organ
- Rostral migratory stream
- 시교차 상핵
- vestibular sensory epithelium
- ventricular zone
- lateral septal nucleus
- 혀의 윗면
- median eminence
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| 추가 참조 발현 데이터 |
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BioGPS |
| 추가 참조 발현 데이터 |
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유전자 온톨로지 |
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분자 함수 | - DNA 결합
- sequence-specific DNA binding
- miRNA binding
- DNA-binding transcription factor activity
- DNA-binding transcription activator activity, RNA polymerase II-specific
- transcription cis-regulatory region binding
- 단백질 결합
- DNA-binding transcription factor activity, RNA polymerase II-specific
| 세포 성분 | - 세포질
- 세포액
- transcription regulator complex
- 핵질
- 세포핵
| 생물학적 과정 | - eye development
- pituitary gland development
- DNA를 주형으로 한 전사의 조절
- negative regulation of neuron differentiation
- somatic stem cell population maintenance
- endodermal cell fate specification
- positive regulation of cell-cell adhesion
- tissue regeneration
- negative regulation of transcription by RNA polymerase II
- chromatin organization
- transcription by RNA polymerase II
- regulation of cysteine-type endopeptidase activity involved in apoptotic process
- adenohypophysis development
- DNA를 주형으로 한 전사
- neuronal stem cell population maintenance
- positive regulation of transcription, DNA-templated
- multicellular organism development
- glial cell fate commitment
- response to wounding
- osteoblast differentiation
- positive regulation of cell differentiation
- negative regulation of epithelial cell proliferation
- 유전자 발현의 조절
- inner ear development
- forebrain development
- response to growth factor
- negative regulation of canonical Wnt signaling pathway
- positive regulation of MAPK cascade
- positive regulation of transcription by RNA polymerase II
- cytokine-mediated signaling pathway
- 세포 분화
- cell fate commitment
- central nervous system development
- neuron differentiation
| 출처: Amigo / QuickGO |
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동원체 |
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종 | 인간 | 쥐 |
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앙트레 | | |
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앙상블 | | |
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유니프롯 | | |
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RefSeq (mRNA) | | |
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RefSeq(단백질) | | |
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위치(UCSC) | Chr 3: 181.71 – 181.71 Mb | Chr 3: 34.7 – 34.71 Mb |
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PubMed 검색 | [3] | [4] |
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위키데이터 |
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