Demoksitocin

IUPAC ime


2-[(1[13-(butan-2-yl)-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl

Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala

Infobox references

pyrrolidin-2-yl)formamido]-N-(carbamoylmethyl)-4-methylpentanamide

|OtherNames= |Section1=! align="center" cellspacing="3" colspan="2" | Identifikacija |-

| CAS registarski broj | 113-78-0 |-

| PubChem^[1]^[2] | 8229 |-

| MeSH | deaminooxytocin |-

| Jmol-3D slike | {{#if:CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCCC(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N|Slika 1 |-

| align="center" colspan="2" |

SMILES
CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCCC(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N

SMILES

CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCCC(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N

| align="center" colspan="2" |

InChI
InChI=1S/C43H65N11O12S2/c1-5-23(4)36-42(65)49-26(12-13-32(44)56)38(61)50-29(19-33(45)57)39(62)52-30(21-68-67-16-14-35(59)48-28(40(63)53-36)18-24-8-10-25(55)11-9-24)43(66)54-15-6-7-31(54)41(64)51-27(17-22(2)3)37(60)47-20-34(46)58/h8-11,22-23,26-31,36,55H,5-7,12-21H2,1-4H3,(H2,44,56)(H2,45,57)(H2,46,58)(H,47,60)(H,48,59)(H,49,65)(H,50,61)(H,51,64)(H,52,62)(H,53,63)^Y Kod: GTYWGUNQAMYZPF-UHFFFAOYSA-N^Y

InChI

InChI=1S/C43H65N11O12S2/c1-5-23(4)36-42(65)49-26(12-13-32(44)56)38(61)50-29(19-33(45)57)39(62)52-30(21-68-67-16-14-35(59)48-28(40(63)53-36)18-24-8-10-25(55)11-9-24)43(66)54-15-6-7-31(54)41(64)51-27(17-22(2)3)37(60)47-20-34(46)58/h8-11,22-23,26-31,36,55H,5-7,12-21H2,1-4H3,(H2,44,56)(H2,45,57)(H2,46,58)(H,47,60)(H,48,59)(H,49,65)(H,50,61)(H,51,64)(H,52,62)(H,53,63)^Y
Kod: GTYWGUNQAMYZPF-UHFFFAOYSA-N^Y

|- |Section2=! align="center" cellspacing="3" colspan="2" | Svojstva |- | Molekulska formula | C₄₃H₆₅N₁₁O₁₂S₂ |- | Molarna masa | 992.17 g mol⁻¹ |- |Section3= }}

Demoksitocin (INN, trgovačko ime Sandopart) ili deaminooksitocin, je akušerski lek koji se koristi za prevenciju postnatalnog mastitisa.^[3]^[4] On je analogan oksitocinu.

Vidi još

Karbetocin
Oksitocin
WAY-267,464

Literatura

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Ulstein M, Sagen N, Eikhom SN (1979). „A comparative study of labor induced by oral prostaglandin E2 and buccal tablets of demoxytocin”. Int J Gynaecol Obstet 17 (3): 243–5. PMID 42577.
↑ Lykkesfeldt G, Osler M (1981). „Induction of labor with oral prostaglandin E2 and buccal demoxytocin without amniotomy”. Acta Obstet Gynecol Scand 60 (4): 429–30. PMID 7282312.