MRGPRX2

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MAS-sličan GPR, član X2

Identifikatori

MRGPRX2; MRGX2

Vanjski ID

OMIM: 607228 MGI: 3588270 HomoloGene: 24986 IUPHAR: MRGPRX2 GeneCards: MRGPRX2 Gene

Ontologija gena
Molekularna funkcija	• rodopsinu-slična receptorska aktivnost • receptorska aktivnost • neuropeptidno vezivanje
Celularna komponenta	• membrana • integralno sa membranom
Biološki proces	• prenos signala • signalni put G-protein spregnutog receptora • senzorska percepcija bola • san

Ortolozi

Vrsta

Čovek

Miš

Entrez

117194

243978

Ensembl

ENSG00000183695

ENSMUST00000098433

UniProt

Q96LB1

Q3UG50

RefSeq (mRNA)

NM_054030

NM_001034868

RefSeq (protein)

NP_473371

NP_001030040

Lokacija (UCSC)

Chr 11:
19.03 - 19.04 Mb

Chr 7:
55.74 - 55.74 Mb

PubMed pretraga

[1]

[2]

MAS-sličan G-protein spregnuti receptor, član X2 je protein koji je kod ljudi kodiran MRGPRX2 genom.^[1]^[2]

Vidi još

↑ Dong X, Han S, Zylka MJ, Simon MI, Anderson DJ (Sep 2001). „A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons”. Cell 106 (5): 619–32. DOI:10.1016/S0092-8674(01)00483-4. PMID 11551509.
↑ „Entrez Gene: MRGPRX2 MAS-related GPR, member X2”.

Takeda S, Kadowaki S, Haga T, et al. (2002). „Identification of G protein-coupled receptor genes from the human genome sequence.”. FEBS Lett. 520 (1-3): 97–101. DOI:10.1016/S0014-5793(02)02775-8. PMID 12044878.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Robas N, Mead E, Fidock M (2004). „MrgX2 is a high potency cortistatin receptor expressed in dorsal root ganglion.”. J. Biol. Chem. 278 (45): 44400–4. DOI:10.1074/jbc.M302456200. PMID 12915402.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Yang S, Liu Y, Lin AA, et al. (2005). „Adaptive evolution of MRGX2, a human sensory neuron specific gene involved in nociception.”. Gene 352: 30–5. DOI:10.1016/j.gene.2005.03.001. PMID 15862286.