Putrescin karbamoiltransferaza
Putrescin karbamoiltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.1.3.6 | ||||||||
CAS broj | 9076-55-5 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Putrescin karbamoiltransferaza (EC 2.1.3.6, PTCaza, putrescinska sintaza, putrescinska transkarbamilaza) je enzim sa sistematskim imenom karbamoil-fosfat:putrescin karbamoiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- karbamoil fosfat + putrescin fosfat + N-karbamoilputrescin
Ovaj biljni enzim takođe katalizuje reakcije EC 2.1.3.3, ornitin karbamoiltransferaze, EC 2.7.2.2, karbamatne kinaze i EC 3.5.3.12, agmatinske deiminaze. On deluje kao putrescinska sintaza, koja konvertuje agmatin [(4-aminobutil)guanidin] i ornitin u putrescin i citrulin, respektivno.
Reference
- ↑ Roon, R.J. and Barker, H.A. (1972). „Fermentation of agmatine in Streptococcus faecalis: occurrence of putrescine transcarbamoylase”. J. Bacteriol. 109: 44-50. PMID 4621632.
- ↑ Srivenugopal, K.S. and Adiga, P.R. (1981). „Enzymic conversion of agmatine to putrescine in Lathyrus sativus seedlings. Purification and properties of a multifunctional enzyme (putrescine synthase)”. J. Biol. Chem. 256: 9532-9541. PMID 6895223.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH Putrescine+carbamoyltransferase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6