CBD-DMH
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| 识别信息 | |
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| CAS号 | 97452-63-6（(−)-enantiomer）  Y |
| PubChem CID |
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| CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA) |
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| 化学信息 | |
| 化学式 | C25H38O2 |
| 摩尔质量 | 370.57 |
| 3D模型（JSmol（英语：JSmol）） |
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CBD-DMH（大麻二酚-二甲基庚基，英語：Cannabidiol-dimethylheptyl，也缩写为DMH-CBD），分子式C25H38O2，是一种人工合成的大麻素，可看做大麻二酚的同系物，其侧链上的戊基被替换成二甲基庚基。[1][2][3][4]
参考文献
- ^ Leite JR, Carlini EA, Lander N, Mechoulam R. Anticonvulsant effects of the (-) and (+)isomers of cannabidiol and their dimethylheptyl homologs. Pharmacology. 1982, 24 (3): 141–6. PMID 7071126. doi:10.1159/000137588.
- ^ Bisogno T, Hanus L, De Petrocellis L, Tchilibon S, Ponde DE, Brandi I, et al. Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. British Journal of Pharmacology. October 2001, 134 (4): 845–52. PMC 1573017
. PMID 11606325. doi:10.1038/sj.bjp.0704327. - ^ Ben-Shabat S, Hanus LO, Katzavian G, Gallily R. New cannabidiol derivatives: synthesis, binding to cannabinoid receptor, and evaluation of their antiinflammatory activity. Journal of Medicinal Chemistry. February 2006, 49 (3): 1113–7. PMID 16451075. doi:10.1021/jm050709m.
- ^ Juknat A, Kozela E, Kaushansky N, Mechoulam R, Vogel Z. Anti-inflammatory effects of the cannabidiol derivative dimethylheptyl-cannabidiol - studies in BV-2 microglia and encephalitogenic T cells. Journal of Basic and Clinical Physiology and Pharmacology. May 2016, 27 (3): 289–96. PMID 26540221. doi:10.1515/jbcpp-2015-0071 .
外部链接
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