Dimetridazole

Chemical compound
  • QP51AA07 (WHO)
Identifiers
  • 1,2-dimethyl-5-nitro-1H-imidazole
CAS Number
  • 551-92-8
PubChem CID
  • 3090
ChemSpider
  • 2980 checkY
UNII
  • K59P7XNB8X
KEGG
  • D07855 checkY
ChEMBL
  • ChEMBL38938 checkY
CompTox Dashboard (EPA)
  • DTXSID5020497 Edit this at Wikidata
ECHA InfoCard100.008.184 Edit this at WikidataChemical and physical dataFormulaC5H7N3O2Molar mass141.130 g·mol−13D model (JSmol)
  • Interactive image
  • Cc1ncc([N](=O)=O)n1C
InChI
  • InChI=1S/C5H7N3O2/c1-4-6-3-5(7(4)2)8(9)10/h3H,1-2H3 checkY
  • Key:IBXPYPUJPLLOIN-UHFFFAOYSA-N checkY
  (verify)

Dimetridazole is a drug that combats protozoan infections. It is a nitroimidazole class drug.[1] It used to be commonly added to poultry feed. This led to it being found in eggs. Because of suspicions of it being carcinogenic its use has been legally limited but it is still found in the eggs.[2][3] It is now banned as a livestock feed additive in many jurisdictions, for example in the European Union,[4] Canada.[5] and the United States.[6] In the US, the Food and Drug Administration bans it for extralabel use[7]

See also

References

  1. ^ Dalton, P. (1996). "Use of dimetridazole in gamebirds". The Veterinary Record. 139 (16): 399. PMID 8913016.
  2. ^ Posyniak A, Semeniuk S, Zmudzki J, Niedzielska J, Biernacki B (1996). "Residues of dimetridazole in eggs after treatment of laying hens". Veterinary Research Communications. 20 (2): 167–74. doi:10.1007/bf00385638. PMID 8711897. S2CID 38729121.
  3. ^ Cannavan A, Kennedy DG (1997). "Determination of dimetridazole in poultry tissues and eggs using liquid chromatography-thermospray mass spectrometry". The Analyst. 122 (9): 963–6. Bibcode:1997Ana...122..963C. doi:10.1039/a703193i. PMID 9374025.
  4. ^ Council Regulation (EEC) No 2377/90 of 26 June 1990 [1]
  5. ^ Canadian Food Inspection Agency update Archived May 7, 2005, at the Wayback Machine
  6. ^ US Food and Drugs Administration, Food Additives Status List [2]
  7. ^ US Food and Drug Administration, Code of Federal Regulations, Title 21, Volume 6, Revised as of April 1, 2020 [3]


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