EMID2

Mammalian protein found in Homo sapiens
COL26A1
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

4AU2, 4AU3, 4BJ3

Identifiers
AliasesCOL26A1, EMI6, EMID2, EMU2, SH2B, collagen type XXVI alpha 1, collagen type XXVI alpha 1 chain
External IDsOMIM: 608927 MGI: 2155345 HomoloGene: 136636 GeneCards: COL26A1
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for COL26A1
Genomic location for COL26A1
Band7q22.1Start101,362,875 bp[1]
End101,559,024 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for COL26A1
Genomic location for COL26A1
Band5|5 G2Start136,770,613 bp[2]
End136,912,063 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • vena cava

  • body of tongue

  • prefrontal cortex

  • right ventricle

  • pylorus

  • Brodmann area 9

  • cardia

  • pons

  • ventral tegmental area

  • inferior ganglion of vagus nerve
Top expressed in
  • dermis

  • vas deferens

  • external carotid artery

  • maxillary prominence

  • internal carotid artery

  • saccule

  • otic placode

  • medullary collecting duct

  • renal corpuscle

  • abdominal wall
More reference expression data
BioGPS




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

136227

140709

Ensembl

ENSG00000160963

ENSMUSG00000004415

UniProt

Q96A83

Q91VF6

RefSeq (mRNA)

NM_133457
NM_001278563

NM_024474
NM_001346699

RefSeq (protein)

NP_001265492
NP_597714

NP_001333628
NP_077794

Location (UCSC)Chr 7: 101.36 – 101.56 MbChr 5: 136.77 – 136.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Collagen alpha-1(XXVI) chain is a protein that in humans is encoded by the EMID2 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000160963 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000004415 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Leimeister C, Steidl C, Schumacher N, Erhard S, Gessler M (Sep 2002). "Developmental expression and biochemical characterization of Emu family members". Dev Biol. 249 (2): 204–18. doi:10.1006/dbio.2002.0764. PMID 12221002.
  6. ^ "Entrez Gene: EMID2 EMI domain containing 2".

Further reading

  • Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Sato K, Yomogida K, Wada T, et al. (2002). "Type XXVI collagen, a new member of the collagen family, is specifically expressed in the testis and ovary". J. Biol. Chem. 277 (40): 37678–84. doi:10.1074/jbc.M205347200. PMID 12145293.
  • Velling T, Kusche-Gullberg M, Sejersen T, Gullberg D (1999). "cDNA cloning and chromosomal localization of human alpha(11) integrin. A collagen-binding, I domain-containing, beta(1)-associated integrin alpha-chain present in muscle tissues". J. Biol. Chem. 274 (36): 25735–42. doi:10.1074/jbc.274.36.25735. PMID 10464311.
  • Rada JA, Cornuet PK, Hassell JR (1996). "Regulation of corneal collagen fibrillogenesis in vitro by corneal proteoglycan (lumican and decorin) core proteins". Exp. Eye Res. 56 (6): 635–48. doi:10.1006/exer.1993.1081. PMID 8595806.
  • Homma N, Gejyo F, Isemura M, Arakawa M (1989). "Collagen-binding affinity of beta-2-microglobulin, a preprotein of hemodialysis-associated amyloidosis". Nephron. 53 (1): 37–40. doi:10.1159/000185699. PMID 2674742.

External links

  • Overview of all the structural information available in the PDB for UniProt: Q96A83 (Collagen alpha-1(XXVI) chain (EMID2)) at the PDBe-KB.
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Extracellular
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Collagen
Fibril forming
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Enzymes
Laminin
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