EIF4G1 |
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Наявні структури |
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PDB | Пошук ортологів: PDBe RCSB | Список кодів PDB | 1LJ2, 1UG3, 2W97, 4AZA, 4F02 | | |
Ідентифікатори |
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Символи | EIF4G1, EIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18, Eukaryotic translation initiation factor 4 gamma, eukaryotic translation initiation factor 4 gamma 1 |
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Зовнішні ІД | OMIM: 600495 MGI: 2384784 HomoloGene: 110725 GeneCards: EIF4G1 |
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Онтологія гена |
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Молекулярна функція | • translation initiation factor activity • GO:0001948, GO:0016582 protein binding • RNA binding • mRNA binding • ATP binding • translation factor activity, RNA binding • eukaryotic initiation factor 4E binding • translation initiation factor binding • GO:0032947 molecular adaptor activity • cadherin binding • identical protein binding |
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Клітинна компонента | • гіалоплазма • мембрана • клітинне ядро • цитоплазма • Полісома • eukaryotic translation initiation factor 4F complex • cytosolic small ribosomal subunit • postsynapse |
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Біологічний процес | • nuclear-transcribed mRNA poly(A) tail shortening • regulation of mRNA stability • behavioral fear response • positive regulation of neuron differentiation • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • GO:0022415 viral process • regulation of translation • regulation of translational initiation • cap-dependent translational initiation • Біосинтез білків • translational initiation • mitochondrion organization • positive regulation of cell population proliferation • negative regulation of autophagy • negative regulation of peptidyl-threonine phosphorylation • positive regulation of cell growth • GO:0051247, GO:0051200 positive regulation of protein metabolic process • GO:0007571 розвойовий процес • positive regulation of peptidyl-serine phosphorylation • cellular macromolecule biosynthetic process • GO:1905616 regulation of gene silencing by miRNA • GO:1904490 regulation of cellular response to stress • positive regulation of G1/S transition of mitotic cell cycle • negative regulation of neuron death • positive regulation of eukaryotic translation initiation factor 4F complex assembly • regulation of presynapse assembly • positive regulation of mRNA cap binding • regulation of polysome binding • positive regulation of cell death • cellular response to nutrient levels • energy homeostasis • lung development • response to ethanol |
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Джерела:Amigo / QuickGO | |
Шаблон експресії |
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Більше даних |
Ортологи |
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Види | Людина | Миша |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (мРНК) | NM_198244 NM_001194946 NM_001194947 NM_001291157 NM_004953
| NM_182917 NM_198241 NM_198242 |
| | NM_001005331 NM_145941 NM_001304432 |
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RefSeq (білок) | NP_001181875 NP_001181876 NP_001278086 NP_004944 NP_886553
| NP_937884 NP_937885 NP_937887 |
| NP_001291361 NP_666053 NP_001390389 NP_001390390 NP_001390391
| NP_001390392 NP_001390393 NP_001390394 NP_001390395 NP_001390396 NP_001390397 |
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Локус (UCSC) | Хр. 3: 184.31 – 184.34 Mb | Хр. 16: 20.49 – 20.51 Mb |
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PubMed search | [1] | [2] |
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Вікідані |
Див./Ред. для людей | Див./Ред. для мишей |
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