Acetoxolutamide
Chemical compound
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Drug class | Nonsteroidal androgen; Selective androgen receptor modulator |
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Formula | C19H18F3N3O6 |
Molar mass | 441.363 g·mol−1 |
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Acetoxolutamide is a nonsteroidal androgen and selective androgen receptor modulator (SARM) which was described in 2000 and was never developed or marketed for medical use.[1] It was derived from structural modification of the nonsteroidal antiandrogen bicalutamide and the nonsteroidal SARM acetothiolutamide.[1] Acetoxolutamide shows greatly improved pharmacokinetic properties and anabolic and androgenic potency relative to acetothiolutamide in animals.[1] It is the (2R) enantiomer of andarine (also known as acetamidoxolutamide or androxolutamide).[1]
References
- ^ a b c d Yin D (December 2000). Pharmacology, Pharmacokinetics and Metabolism of Nonsteroidal Androgens (Ph.D. thesis). The University of Tennessee Health Science Center. ProQuest 304669272.
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- See also
- Receptor/signaling modulators
- Androgens and antiandrogens
- Estrogen receptor modulators
- Progesterone receptor modulators
- List of androgens and anabolic steroids
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