Formyl-CoA hydrolase

formyl-CoA hydrolase
Identifiers
EC no.3.1.2.10
CAS no.9025-91-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
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The enzyme formyl-CoA hydrolase (EC 3.1.2.10) catalyzes the reaction

formyl-CoA + H2O {\displaystyle \rightleftharpoons } CoA + formate

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name is formyl-CoA hydrolase. This enzyme is also called formyl coenzyme A hydrolase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

  • Sly WS, Stadtman ER (August 1963). "Formate metabolism. I. Formyl coenzyme A, an intermediate in the formate-dependent decomposition of acetyl phosphate in Clostridium kluyveri". The Journal of Biological Chemistry. 238: 2632–8. PMID 14063284.
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3.1.1: Carboxylic
ester hydrolases
3.1.2: Thioesterase
3.1.3: Phosphatase
3.1.4:
Phosphodiesterase
3.1.6: Sulfatase
Nuclease (includes
deoxyribonuclease
and ribonuclease)
3.1.11-16:
Exonuclease
Exodeoxyribonuclease
Exoribonuclease
3.1.21-31:
Endonuclease
Endodeoxyribonuclease
Endoribonuclease
either deoxy- or ribo-    
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