L-687,384
 | |
| IUPAC ime | |
|---|---|
1'-benzylspiro[2,3-dihydro-1H-naphthalene-4,4'-piperidine] | |
| Identifikatori | |
| CAS broj | 95417-67-7  Y |
| ATC kod | none |
| PubChem | CID 125328 |
| Hemijski podaci | |
| Formula | C21H25N |
| Molarna masa | 291.429 g/mol |
SMILES
| |
L-687,384 je agonist sigma receptora. On je selektivan za σ1 tip.[1] On je isto tako NMDA antagonist.[2]
Reference
- ^ Bergeron R, Debonnel G (1997). „Effects of low and high doses of selective sigma ligands: further evidence suggesting the existence of different subtypes of sigma receptors”. Psychopharmacology. 129 (3): 215—24. PMID 9084059.
- ^ McLarnon J, Sawyer D, Church J (1994). „The actions of L-687,384, a sigma receptor ligand, on NMDA-induced currents in cultured rat hippocampal pyramidal neurons”. Neuroscience Letters. 174 (2): 181—4. PMID 7526288.
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Modulatori sigma receptora
- Agonisti: 3-PPP
- 4-PPBP
- 5-MeO-DMT
- Alazocin (SKF-10047)
- Amantadin
- ANAVEX2-73
- Arketamin
- BD-737
- BD-1052
- Kaptodiam
- Citalopram
- CGRP
- Kloperastin
- Kokain
- Kutamezin (SA-4503)
- Ciklazocin
- Dehidroepiandrosteron (DHEA) (prasteron)
- Dehidroepiandrosteron sulfat (DHEA-S) (prasteron sulfat)
- Dekstralorfan
- Dekstrometorfan (DXM)
- Dekstrorfan (DXO)
- Dimemorfan
- Dimetiltriptamin (DMT)
- Ditolilgvanidin (DTG)
- Donepezil
- Eliprodil
- Escitalopram
- Fabomotizol (afobazol)
- Fluoksetin
- Fluvoksamin
- Ifenprodil
- Igmesin (JO-1784)
- IPAB
- Ketamin
- L-687384
- MDMA (midomafetamin)
- Memantin
- Metamfetamin
- Metoksetamin
- Metilfenidat
- Nepinalon
- Neuropeptid Y
- Noskapin
- OPC-14523
- Opipramol
- Pentazocin
- Pentoksiverin (karbetapentan)
- PRE-084
- Pregnenolon
- Pregnenolon sulfat
- Pridopidin
- Racemetorfan (metorfan)
- Racemorfan (morfanol)
- UMB-23
- UMB-82
- Antagonisti: 3-PPP
- AC-927
- BD-1008
- BD-1031
- BD-1047
- BD-1060
- BD-1063
- BD-1067
- BMY-14802 (BMS-181100)
- CM-156
- Dup-734
- E-5842
- E-52862 (S1RA)
- Haloperidol
- LR-132
- LR-172
- MS-377
- NE-100
- NPC-16377
- Panamesin (EMD-57455)
- PD-144418
- Pentazocin
- Progesteron
- Rimkazol (BW-234U)
- Sertralin
- SR-31742A
- Alosterni modulatori: Fenitoin; Pozitivni: Metilfenilpiracetam
- SOMCL-668
- Nepoznati/nerazvrstani: 3-Metoksidekstralorfan
- 3-MeO-PCP
- 4C-T-2
- 4-IBP
- 4-IPBS
- 4-MeO-PCP
- 5-MeO-DALT
- 5-MeO-DiPT
- Amitriptilin
- Azidopamil
- Hlorpromazin
- Klemastin
- Klomipramin
- Klorgilin
- D-Deprenil
- DiPT
- DPT
- Ibogain
- Imipramin
- KCR-12-83.1
- Nemonaprid
- Noribogain
- RHL-033
- RS-67,333
- RTI-55
- Šafran
- Safinamid
- Selegilin
- Spipetijan
- Trifluoperazin
- W-18
- YKP10A
- Agonisti: 3-PPP
- Arketamin
- BD-1047
- BD1063
- Ditolilgvanidin (DTG)
- DKR-1005
- DKR-1051
- Haloperidol
- Ifenprodil
- Ketamin
- MDMA (midomafetamin)
- Metamfetamin
- OPC-14523
- Opipramol
- PB-28
- Fenciklidin
- Siramesin (Lu 28-179)
- UKH-1114
- Antagonisti: AC-927
- BD-1008
- BD-1067
- CM-156
- CT-1812
- LR-172
- MIN-101
- Panamesin (EMD-57455)
- SAS-0132
- Nepoznati/nerazvrstani: 3-Metoksidekstralorfan
- 3-MeO-PCE
- 4-MeO-PCP
- 5-MeO-DALT
- 5-MeO-DiPT
- Klemastin
- DiPT
- DPT
- Ibogain
- Nemonaprid
- Nepinalon
- Noribogain
- Pentazocin
- RS-67,333
- Safinamid
- TMA
- UMB-23
- UMB-82
- W-18
vrstani
- Agonisti: Berberin
- Etilketazocin
- Forfit
- Metafit
- Nalbufin
- Naluzotan
- Tapentadol
- Tenociklidin
- Antagonisti: AHD1
- AZ66
- Lamotrigin
- Nalokson
- SM-21
- UMB-100
- UMB-101
- UMB-103
- UMB-116
- YZ-011
- YZ-069
- YZ-185
- Alosterni modulatori: SKF-83959
- Nepoznati/nerazvrstani: 18-Metoksikoronaridin
- BMY-13980
- Butaklamol
- Karamifen
- Karvotrolin
- Hlorfenamin (hlorfeniramin)
- Hlorpromazin
- Cinarizin
- Cinuperon
- Klocapramin
- Dezocin
- EMD-59983
- Hipericin (kantarion)
- Flufenazin
- Gevotrolin (WY-47384)
- Mepiramin (pirilamin)
- Molindon
- Perfenazin
- Pimozid
- Proadifen
- Prometazin
- Propranolol
- Hinidin
- Remoksiprid
- SL 82.0715
- SR-31747A
- Tiospiron (BMY-13859)
- Venlafaksin
Portali:
Medicina
Hemija
