Eprazinone
Chemical compound
- R05CB04 (WHO)
- 3-[4-(2-ethoxy-2-phenyl-ethyl)piperazin-1-yl]-2-methyl-1-phenyl-propan-1-one
- 10402-90-1
N
- 3245
- DB08990 N
- 3132 N
- 883YNL63WU
- D07902
Y
- CHEBI:82716 N
- DTXSID1048336
- Interactive image
- CCOC(CN1CCN(CC1)CC(C)C(=O)C2=CC=CC=C2)C3=CC=CC=C3
InChI
- InChI=1S/C24H32N2O2/c1-3-28-23(21-10-6-4-7-11-21)19-26-16-14-25(15-17-26)18-20(2)24(27)22-12-8-5-9-13-22/h4-13,20,23H,3,14-19H2,1-2H3N
- Key:BSHWLCACYCVCJE-UHFFFAOYSA-NN
N
Y (what is this?) (verify)Eprazinone (trade names Eftapan, Isilung, Mucitux) is a mucolytic and bronchospasm relieving drug.[1] It has been marketed in many European countries, but not in the US or United Kingdom.[2]
Indications
Indications include acute and chronic bronchitis, cough, rhinitis, and asthma.[2]
Side effects
Adverse effects include headache, somnolence, vertigo, heartburn, and nausea.[2]
References
- ^ Spitzer W (June 1980). "[The efficacy of eprazinone dihydrochloride (Eftapan) in double-blind studies]". Fortschritte der Medizin. 98 (22): (871-4). PMID 6997154.
- ^ a b c Schlesser JL (1991). Drugs Available Abroad, 1st Edition. Derwent Publications Ltd. p. 76. ISBN 0-8103-7177-4.
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Cough and cold preparations (R05)
- Acetylcysteine#
- Ambroxol
- Bromhexine
- Carbocisteine
- Dembrexine hydrochloride
- Domiodol
- Dornase alfa
- Eprazinone
- Erdosteine
- Letosteine
- Mannitol
- Mesna
- Neltenexine
- Sobrerol
- Stepronin
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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