Metocurine

Chemical compound

Metocurine
Identifiers

IUPAC name (1β)-6,6',7',12'-tetramethoxy-2,2,2',2'-tetramethyltubocuraran-2,2'-diium
CAS Number	5152-30-7
PubChem CID	21233
DrugBank	DB01336
ChemSpider	19961
UNII	V0M92G2U26
ChEMBL	ChEMBL1259^Y
CompTox Dashboard (EPA)	DTXSID0048262
Chemical and physical data
Formula	C₄₀H₄₈N₂O₆
Molar mass	652.832 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C[N+]1(CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C6[C@@H](CC7=CC(=C(C=C7)OC)O3)[N+](CCC6=CC(=C5OC)OC)(C)C)OC)C

Metocurine is a muscle relaxant through neuromuscular blockade.^[1] It is excreted entirely through the kidneys and therefore should not be used in patients with kidney failure.

References

^ Fogdall RP (February 1978). "Anesthesiology-epitomes of progress: metocurine-a ;new' muscle relaxant". The Western Journal of Medicine. 128 (2): 148–9. PMC 1238025. PMID 18748141.

Skeletal muscle relaxants (M03)

Peripherally acting
(primarily antinicotinic,
NMJ block)

Non-depolarizing

Curare alkaloids	Alcuronium Dimethyltubocurarine Tubocurarine
4° ammonium agents	ultra-short duration: Gantacurium short duration: Rapacuronium Mivacurium Chandonium intermediate duration: Atracurium Cisatracurium Fazadinium Rocuronium Vecuronium long duration: Doxacurium Dimethyltubocurarine Pancuronium Pipecuronium Laudexium Gallamine unsorted: Hexafluronium (Hexafluorenium)

Depolarizing

Choline derivatives: Suxamethonium (Succinylcholine)

Polyalkylene derivatives: Hexamethonium

ACh release inhibitors

Botulinum toxin

Centrally acting

Carbamic acid esters	Carisoprodol Cyclarbamate Difebarbamate Febarbamate Meprobamate Phenprobamate Styramate Tybamate
Benzodiazepines	Bromazepam Diazepam Clonazepam Flunitrazepam Lorazepam Nitrazepam Temazepam Tetrazepam
Nonbenzodiazepines	Eszopiclone
Thienodiazepines	Etizolam
Quinazolines	Methaqualone
Anticholinergics (Antimuscarinics)	Cyclobenzaprine Orphenadrine
Other	Arbaclofen placarbil Baclofen Chlormezanone Chlorphenesin Chlorzoxazone Eperisone Fenyramidol Flopropione Gabapentin GHB Inaperisone Lanperisone Mephenesin Mephenoxalone Metaxalone Methocarbamol Phenibut Pregabalin Pridinol Promoxolane Quinine Silperisone Thiocolchicoside Tizanidine Tolperisone Zoxazolamine