1,2-Didehydro-3-oxo-THCO
Synthetic cannabinoid
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PubChem CID |
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Chemical and physical data | |
Formula | C24H32O3 |
Molar mass | 368.517 g·mol−1 |
3D model (JSmol) |
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InChI
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1,2-Didehydro-3-oxo-THCO (1,2-Didehydro-3-oxo-Δ8-tetrahydrocannabioctyl) is a semi-synthetic cannabinoid first synthesised by Raj K Razdan et al. in the 1970s, with potent cannabinoid effects.[1][2][3]
See also
- 3'-Hydroxy-THC
- AM-905
- Cannabicyclohexanol
- JWH-138
- Parahexyl
- Tetrahydrocannabihexol
- THCP
References
- ^ Razdan RK, Dalzell HC, Herlihy P, Howes JF (November 1976). "Hashish. Unsaturated side-chain analogues of delta8-tetrahydrocannabinol with potent biological activity". Journal of Medicinal Chemistry. 19 (11): 1328–30. doi:10.1021/jm00233a014. PMID 1003411.
- ^ Razdan RK (January 1981). "The Total Synthesis of Cannabinoids.". In ApSimon J (ed.). Total Synthesis of Natural Products. Vol. 4. John Wiley & Sons. pp. 185–262. doi:10.1002/9780470129678.ch2. ISBN 978-0-470-12953-1.
- ^ US 4036857, Razdan RK, Dalzell HC, "Benzopyrans having an unsaturated side chain.", issued 19 July 1977, assigned to Sharps Associates
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Cannabinoids
(comparison)
Cannabibutols |
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Cannabichromenes | |
Cannabicyclols |
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Cannabidiols | |
Cannabielsoins |
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Cannabigerols | |
Cannabiphorols |
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Cannabinols | |
Cannabitriols |
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Cannabivarins |
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Delta-8-tetrahydrocannabinols |
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Delta-9-tetrahydrocannabinols | |
Delta-10-Tetrahydrocannabinols | |
Miscellaneous cannabinoids |
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Active metabolites |
- Arachidonoyl ethanolamide (AEA; anandamide)
- 2-Arachidonoylglycerol (2-AG)
- 2-Arachidonyl glyceryl ether (2-AGE; noladin ether)
- 2-Oleoylglycerol (2-OG)
- N-Arachidonoyl dopamine (NADA)
- N-Arachidonylglycine (NAGly)
- 2-Arachidonoyl lysophosphatidylinositol (2-ALPI)
- N-Arachidonoyl serotonin (AA-5-HT)
- Docosatetraenoylethanolamide (DEA)
- Lysophosphatidylinositol (LPI)
- Oleamide
- Oleoylethanolamide (OEA)
- Palmitoylethanolamide (PEA)
- RVD-Hpα
- Stearoylethanolamide (SEA)
- O-Arachidonoyl ethanolamine (O-AEA; virodhamine)
cannabinoid
receptor
agonists /
neocannabinoids
enhancers
(inactivation inhibitors)
- 4-Nonylphenylboronic acid
- AM-404
- Arachidonoyl serotonin
- Arvanil
- BIA 10-2474
- Biochanin A
- CAY-10401
- CAY-10429
- Genistein
- Guineesine
- IDFP
- JNJ 1661010
- JNJ-42165279
- JZL184
- JZL195
- Kaempferol
- LY-2183240
- MK-4409
- O-1624
- O-2093
- Oleoylethanolamide (OEA)
- Olvanil
- Palmitoylethanolamide (PEA)
- PF-04457845
- PF-622
- PF-750
- PF-3845
- PHOP
- URB-447
- URB-597
- URB-602
- URB-754
- VDM-11
(antagonists/inverse
agonists/antibodies)
- AM-251
- AM-281
- AM-630
- AM-1387
- AM-4113
- AM-6527
- AM-6545
- BML-190
- Brizantin (Бризантин)
- CAY-10508
- CB-25
- CB-52
- CB-86
- Dietressa (Диетресса)
- Drinabant (AVE1625)
- Hemopressin
- Ibipinabant (SLV319)
- JTE-907
- LH-21
- LY-320,135
- MDA-77
- MJ-15
- MK-9470
- NESS-0327
- NIDA-41020
- O-606
- O-1184
- O-1248
- O-1918
- O-2050
- O-2654
- Otenabant (CP-945,598)
- PF-514273
- PipISB
- PSB-SB-487
- Rimonabant (SR141716)
- Rosonabant (E-6776)
- SR-144,528
- Surinabant (SR147778)
- Taranabant (MK-0364)
- TM-38837
- VCHSR
- See also: Cannabinoid receptor modulators (cannabinoids by pharmacology)
- List of: AM cannabinoids
- JWH cannabinoids
- Designer drugs § Synthetic cannabimimetics
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