Arisugacin A
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Preferred IUPAC name (4aR,6aR,12aS,12bS)-9-(3,4-Dimethoxyphenyl)-4a,12a-dihydroxy-4,4,6a,12b-tetramethyl-4a,6,6a,12,12a,12b-hexahydro-4H,11H-naphtho[2,1-b]pyrano[3,4-e]pyran-1,11(5H)-dione | |
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Chemical formula | C28H32O8 |
Molar mass | 496.556 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
Arisugacin A is an orally active acetylcholinesterase inhibitor.[2]
References
- ^ "KNApSAcK Metabolite Information - C00016246". www.knapsackfamily.com.
- ^ Sunazuka, T; Handa, M; Nagai, K; Shirahata, T; Harigaya, Y; Otoguro, K; Kuwajima, I; Omura, S (2002). "The first total synthesis of (+/-)-arisugacin A, a potent, orally bioavailable inhibitor of acetylcholinesterase". Organic Letters. 4 (3): 367–9. doi:10.1021/ol017046x. PMID 11820881.
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Acetylcholine metabolism and transport modulators
(modulators)
(modulators)
CHTTooltip Choline transporter |
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VAChTTooltip Vesicular acetylcholine transporter |
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(modulators)
Inhibitors |
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Enhancers |
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- See also
- Receptor/signaling modulators
- Muscarinic acetylcholine receptor modulators
- Nicotinic acetylcholine receptor modulators
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