Ro 3-0412
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Preferred IUPAC name 3-[(Dimethoxyphosphoryl)oxy]-N,N,N-trimethylanilinium methyl sulfate | |
Other names Dimethylphosphostigmine | |
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Chemical formula | C12H22NO8PS |
Molar mass | 371.34 g·mol−1 |
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Lethal dose or concentration (LD, LC): | |
LD50 (median dose) | 0.57 mg/kg (mice, intravenous) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
Ro 3-0412 is an acetylcholinesterase inhibitor. It is the organophosphate analog of neostigmine.[1]
See also
- Neostigmine
- Ro 3-0419
- Ro 3-0422
References
- ^ BURGEN, AS; HOBBIGER, F (December 1951). "The inhibition of cholinesterases by alkyl-phosphates and alkylphenolphosphates". British Journal of Pharmacology and Chemotherapy. 6 (4): 593–605. doi:10.1111/j.1476-5381.1951.tb00670.x. PMC 1509150. PMID 14904884.
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(modulators)
(modulators)
CHTTooltip Choline transporter |
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VAChTTooltip Vesicular acetylcholine transporter |
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(modulators)
Inhibitors |
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Enhancers |
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- See also
- Receptor/signaling modulators
- Muscarinic acetylcholine receptor modulators
- Nicotinic acetylcholine receptor modulators
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