Buthalital
Chemical compound
- None
- sodium 5-allyl-5-isobutyl-6-oxo-2-thioxo-1,2,5,6-tetrahydro-4-pyrimidinolate
- 510-90-7
468-65-5 (no salt)
- 3032320
- 2297324
- 810E8N9VUG
- ChEMBL2106716
- DTXSID40965285
- Interactive image
- [Na+].O=C1NC(=S)/N=C(/[O-])C1(CC(C)C)C\C=C
InChI
- InChI=1S/C11H16N2O2S.Na/c1-4-5-11(6-7(2)3)8(14)12-10(16)13-9(11)15;/h4,7H,1,5-6H2,2-3H3,(H2,12,13,14,15,16);/q;+1/p-1
- Key:APSWQQYXFMUODF-UHFFFAOYSA-M
Buthalital sodium (INN; Bayinal, Baytinal, Thialbutal, Transithal, Ulbreval), or buthalitone sodium (BAN), is a barbiturate derivative which was under development as a short-acting anesthetic.[1][2] However, development was discontinued, perhaps due to its extremely rapid elimination rate,[3] and buthalital sodium was never marketed.[1]
See also
- Barbiturate
References
- ^ a b Macdonald F (1997). Dictionary of Pharmacological Agents. CRC Press. p. 338. ISBN 978-0-412-46630-4. Retrieved 19 May 2012.
- ^ Martin JR, Godel T, Hunkeler W, Jenck F, Moreau JL, Sleight AJ, Widmer U (2000). "Psychopharmacological Agents". Kirk-Othmer Encyclopedia of Chemical Technology. doi:10.1002/0471238961.1619250313011820.a01. ISBN 0471238961.
- ^ Wollweber H (2000). "Anesthetics, General". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a02_289. ISBN 978-3527306732.
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General anesthetics (N01A)
| Phenols | |
|---|---|
| Barbiturates | |
| Benzodiazepines | |
| Opioids | |
| Arylcyclohexylamines | |
| Neuroactive steroids | |
| Others |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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