2-Amino-1,2-dihydronaphthalene

Chemical compound
  • none
Legal statusLegal status
  • In general: uncontrolled
Identifiers
  • 1,2-dihydronaphthalen-2-amine
CAS Number
  • 79605-60-0 ☒N
PubChem CID
  • 133605
ChemSpider
  • 117856 checkY
CompTox Dashboard (EPA)
  • DTXSID501001767 Edit this at Wikidata
Chemical and physical dataFormulaC10H11NMolar mass145.205 g·mol−13D model (JSmol)
  • Interactive image
  • c2ccc1c(\C=C/C(N)C1)c2
InChI
  • InChI=1S/C10H11N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-6,10H,7,11H2 checkY
  • Key:SHLZSYAMFQNEOF-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

2-Amino-1,2-dihydronapthalene (2-ADN), also known as 2-aminodilin (2-AD), is a stimulant drug.[1] It is a rigid analogue of phenylisobutylamine and substitutes for amphetamine in rat discrimination tests, although at approximately one fourth the potency.[1] It is closely related to 2-aminotetralin (2-amino-1,2,3,4-tetrahydronaphthalene), which also substitutes for amphetamine, and is about two times as potent in comparison.[1]

See also

  • 2-Aminoindane
  • 2-Aminotetralin
  • 2-Naphthylamine

References

  1. ^ a b c Hathaway BA, Nichols DE, Nichols MB, Yim GK (May 1982). "A new, potent, conformationally restricted analogue of amphetamine: 2-amino-1,2-dihydronaphthalene". Journal of Medicinal Chemistry. 25 (5): 535–8. doi:10.1021/jm00347a011. PMID 6123601.
  • v
  • t
  • e
AdamantanesAdenosine antagonistsAlkylaminesAmpakinesArylcyclohexylaminesBenzazepinesCathinonesCholinergicsConvulsantsEugeroicsOxazolinesPhenethylamines
PhenylmorpholinesPiperazinesPiperidinesPyrrolidinesRacetamsTropanesTryptaminesOthers
  • v
  • t
  • e
DRAsTooltip Dopamine releasing agents
NRAsTooltip Norepinephrine releasing agents
SRAsTooltip Serotonin releasing agents
Others
See also: Receptor/signaling modulators • Monoamine reuptake inhibitors • Adrenergics • Dopaminergics • Serotonergics • Monoamine metabolism modulators • Monoamine neurotoxins