Glafenine
Chemical compound
- N02BG03 (WHO)
- 2,3-Dihydroxypropyl 2-[(7-chloro-4-quinolinyl)amino]benzoate
- 3820-67-5
- 3474
- 3355
- 46HL4I09AH
- CHEBI:31653 Y
- ChEMBL146095
- DTXSID1048546
- Interactive image
- O=C(OCC(O)CO)c1ccccc1Nc2c3ccc(Cl)cc3ncc2
InChI
- InChI=1S/C19H17ClN2O4/c20-12-5-6-14-17(7-8-21-18(14)9-12)22-16-4-2-1-3-15(16)19(25)26-11-13(24)10-23/h1-9,13,23-24H,10-11H2,(H,21,22)
- Key:GWOFUCIGLDBNKM-UHFFFAOYSA-N
Glafenine is a nonsteroidal anti-inflammatory drug (NSAID). Use of glafenine is limited due to the risk of anaphylaxis and acute kidney failure.[1][2]
See also
- Floctafenine, a chemically related NSAID
References
- ^ "Withdrawal of glafenine". The Lancet. 339 (8789): 357. 1992. doi:10.1016/0140-6736(92)91670-4. S2CID 54255503.
- ^ Kleinknecht D, Landais P, Goldfarb B (June 1986). "Analgesic and non-steroidal anti-inflammatory drug-associated acute renal failure: a prospective collaborative study". Clinical Nephrology. 25 (6): 275–81. PMID 2873910.
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modulators
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Sodium blockers |
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Potassium openers |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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