Corbadrine
Chemical compound
- none
- In general: ℞ (Prescription only)
- 4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol
- 829-74-3
Y
- 164739
- 508
- DB06707 Y
- 144416 Y
- V008L6478D
- D02388 Y
- ChEMBL677 Y
- DTXSID6046349
- Interactive image
- Oc1ccc(cc1O)[C@@H](O)[C@@H](N)C
InChI
- InChI=1S/C9H13NO3/c1-5(10)9(13)6-2-3-7(11)8(12)4-6/h2-5,9,11-13H,10H2,1H3/t5-,9-/m0/s1Y
- Key:GEFQWZLICWMTKF-CDUCUWFYSA-NY
N
Y (what is this?) (verify)Corbadrine (INN; marketed as Neo-Cobefrine), also known as levonordefrin (USAN) and α-methylnorepinephrine, is a catecholamine sympathomimetic used as a topical nasal decongestant and vasoconstrictor in dentistry in the United States,[1][2] (usually in a pre-mixed solution with local anesthetics, such as mepivacaine).[3]
Corbadrine is also a metabolite of the antihypertensive drug methyldopa,[4] and plays a role in its pharmacology and effects.
See also
References
- ^ Morton I, Morton IK, Hall JM (31 October 1999). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 164–. ISBN 978-0-7514-0499-9.
- ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 275–. ISBN 978-3-88763-075-1.
- ^ "DailyMed — Search results for levonordefrin". DailyMed. Retrieved 20 February 2016.
- ^ Sjoerdsma A, Vendsalu A, Engelman K (October 1963). "Studies on the Metabolism and Mechanism of Action of Methyldopa". Circulation. 28 (4): 492–502. doi:10.1161/01.CIR.28.4.492. PMID 14068757.
External links
- Nordefrin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- v
- t
- e
Decongestants and other nasal preparations (R01)
| Sympathomimetics, plain | |
|---|---|
| Antiallergic agents, excluding corticosteroids | |
| Corticosteroids | |
| Other nasal preparations | |
| Combination products |
Sympathomimetics
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
 | This drug article relating to the respiratory system is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e
