Chloroprednisone acetate

Chemical compound
Chloroprednisone acetate
Clinical data
Trade namesLocalyn, Adremycine, Topilan
Other namesChloroprednisone 21-acetate
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • [2-[(6S,8S,9S,10R,13S,14S,17R)-6-Chloro-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
CAS Number
  • 14066-79-6
PubChem CID
  • 235970
UNII
  • Z243A6BHCS
ECHA InfoCard100.034.458 Edit this at Wikidata
Chemical and physical data
FormulaC23H27ClO6
Molar mass434.91 g·mol−1
3D model (JSmol)
  • Interactive image
  • CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2C[C@@H](C4=CC(=O)C=C[C@]34C)Cl)C)O
InChI
  • InChI=1S/C23H27ClO6/c1-12(25)30-11-19(28)23(29)7-5-15-14-9-17(24)16-8-13(26)4-6-21(16,2)20(14)18(27)10-22(15,23)3/h4,6,8,14-15,17,20,29H,5,7,9-11H2,1-3H3/t14-,15-,17-,20+,21-,22-,23-/m0/s1
  • Key:RACDDTQBAFEERP-PLTZVPCUSA-N

Chloroprednisone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It is the 21-acetate ester of chloroprednisone.[1]

References

  1. ^ Elks J (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 252.
  • v
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Glucocorticoid receptor modulators
GRTooltip Glucocorticoid receptor
Agonists
  • Nonsteroidal glucocorticoids: AZD-5423
  • GSK-9027
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others
  • Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)
See also
Receptor/signaling modulators
Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids


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