Tixocortol pivalate
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| Names | |
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| IUPAC name S-(11β,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl) 2,2-dimethylpropanethioate | |
| Systematic IUPAC name S-{2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-Dihydroxy-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl} 2,2-dimethylpropanethioate | |
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CAS Number |
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3D model (JSmol) |
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| ECHA InfoCard | 100.054.261  |
PubChem CID |
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CompTox Dashboard (EPA) |
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| Properties | |
Chemical formula | C26H38O5S |
| Molar mass | 462.64 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).  N verify (what is  Y N ?) Infobox references | |
Chemical compound
Tixocortol pivalate is a corticosteroid. It has anti-inflammatory properties similar to hydrocortisone.[1] It is marketed under the brand name Pivalone.[2]
It is sometimes used in patch testing in atopic dermatitis.[3]
See also
- Tixocortol
References
- ^ P Larochelle MD, PhD; P Du Souich MD, PhD; E Bolte MD; J Lelorier MD, PhD & R Goyer PhD (1983). "Tixocortol pivalate, a corticosteroid with no systemic glucocorticoid effect after oral, intrarectal, and intranasal application". Clinical Pharmacology and Therapeutics. 33 (3): 343–350. doi:10.1038/clpt.1983.43. PMID 6402333. S2CID 29876079. Retrieved 2011-03-29.
- ^ "Tixocortol Pivalate". Drugs.com. Retrieved 2011-03-29.
- ^ Nedorost ST, Babineau D (October 2010). "Patch testing in atopic dermatitis". Dermatitis. 21 (5): 251–4. doi:10.2310/6620.2010.10036. PMID 20920410. S2CID 25026888.
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Glucocorticoids and antiglucocorticoids (D07, H02)
| Natural | |
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| Synthetic |
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- Antagonists: Aglepristone
- Ketoconazole
- Mifepristone
- Ulipristal acetate
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
- See also
- Glucocorticoid receptor modulators
- Mineralocorticoids and antimineralocorticoids
- List of corticosteroids
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