Desoximetasone

Chemical compound
  • D07AC03 (WHO)
    D07XC02 (WHO) (combinations)
Legal statusLegal status
  • In general: ℞ (Prescription only)
Identifiers
  • (8S,9S,10S,11S,13S,14S,16R,17S)-9-Fluoro-11- hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl- 7,8,11,12,14,15,16,17-octahydro-6H- cyclopenta[a]phenanthren-3-one
CAS Number
  • 382-67-2 checkY
PubChem CID
  • 5311067
IUPHAR/BPS
  • 7067
DrugBank
  • DB00547 checkY
ChemSpider
  • 21117768 checkY
UNII
  • 4E07GXB7AU
KEGG
  • D03697 checkY
ChEMBL
  • ChEMBL1766 ☒N
CompTox Dashboard (EPA)
  • DTXSID3045647 Edit this at Wikidata
ECHA InfoCard100.006.224 Edit this at WikidataChemical and physical dataFormulaC22H29FO4Molar mass376.468 g·mol−13D model (JSmol)
  • Interactive image
  • OCC(=O)[C@H]3[C@H](C)CC2C4CC/C1=C/C(=O)\C=C/[C@]1(C)[C@@]4(F)[C@@H](O)C[C@@]23C
InChI
  • InChI=1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15?,16?,18+,19-,20+,21+,22+/m1/s1 checkY
  • Key:VWVSBHGCDBMOOT-ZIKVJHDZSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Desoximetasone is a medication belonging to the family of medications known as topical corticosteroids. It is used for the relief of various skin conditions, including rashes. It helps to reduce redness, itching, and irritation.[1] Desoximetasone is a synthetic corticosteroid, a class of primarily synthetic steroids used as anti-inflammatory and anti-pruritic agents.

Three brand name products are available (availability depending on country):

  • Topicort Emollient Cream (0.25% desoximetasone)
  • Topicort LP Emollient Cream (0.05% desoximetasone)
  • Topisolone Cream (0.25% desoximetasone)

Usage

When using desoximetasone, some of the medication may be absorbed through the skin and into the bloodstream. Too much absorption can lead to unwanted side effects elsewhere in the body. Large amounts of desoximetasone should be avoided over large areas. It should not be used for extended periods of time. Treated areas should not be covered with airtight dressings such as plastic wrap or adhesive bandages.[1] Children may absorb more medication than adults do. Desoximetasone is for use only on the skin and should be kept out of the eyes.

Desoximetasone can also be used to treat some types of psoriasis.

See also

References

  1. ^ a b "Desoximetasone Topical". Medline Plus. U.S. National Library of Medicine.

External links

  • Topicort general info
  • Topicort usage info
  • v
  • t
  • e
Glucocorticoids
Natural
Synthetic
AntiglucocorticoidsSynthesis modifiers
See also
Glucocorticoid receptor modulators
Mineralocorticoids and antimineralocorticoids
List of corticosteroids
  • v
  • t
  • e
GRTooltip Glucocorticoid receptor
Agonists
  • Nonsteroidal glucocorticoids: AZD-5423
  • GSK-9027
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others
  • Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)
See also
Receptor/signaling modulators
Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids