BCL6 |
---|
|
Наявні структури |
---|
PDB | Пошук ортологів: PDBe RCSB | Список кодів PDB | 1R28, 1R29, 1R2B, 2EN2, 2EOS, 2LCE, 2YRM, 3BIM, 3E4U, 3LBZ, 4CP3, 4U2M | | |
Ідентифікатори |
---|
Символи | BCL6, BCL5, BCL6A, LAZ3, ZBTB27, ZNF51, B-cell CLL/lymphoma 6, B cell CLL/lymphoma 6, transcription repressor, BCL6 transcription repressor |
---|
Зовнішні ІД | OMIM: 109565 MGI: 107187 HomoloGene: 7640 GeneCards: BCL6 |
---|
Онтологія гена |
---|
Молекулярна функція | • sequence-specific DNA binding • DNA binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • intronic transcription regulatory region sequence-specific DNA binding • chromatin binding • зв'язування з іоном металу • GO:0001948, GO:0016582 protein binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • nucleic acid binding • chromatin DNA binding • identical protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific |
---|
Клітинна компонента | • replication fork • клітинне ядро • нуклеоплазма • комплекс Ґольджі |
---|
Біологічний процес | • regulation of germinal center formation • positive regulation of histone deacetylation • negative regulation of T-helper 2 cell differentiation • GO:0034613 protein localization • negative regulation of mast cell cytokine production • GO:0009373 regulation of transcription, DNA-templated • процес імунної системи • GO:0043087, GO:0032313, GO:0032319, GO:0032314, GO:0043088 regulation of GTPase activity • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • negative regulation of cell differentiation • germinal center formation • negative regulation of Rho protein signal transduction • negative regulation of isotype switching to IgE isotypes • negative regulation of apoptotic process • GO:1901227 negative regulation of transcription by RNA polymerase II • transcription, DNA-templated • type 2 immune response • cellular response to DNA damage stimulus • negative regulation of cell-matrix adhesion • regulation of cell population proliferation • positive regulation of B cell proliferation • negative regulation of cell growth • Rho protein signal transduction • GO:0000767 cell morphogenesis • Сперматогенез • regulation of memory T cell differentiation • positive regulation of neuron differentiation • regulation of inflammatory response • regulation of immune response • positive regulation of apoptotic process • negative regulation of type 2 immune response • negative regulation of B cell apoptotic process • B cell differentiation • inflammatory response • GO:0045996 negative regulation of transcription, DNA-templated • actin cytoskeleton organization • negative regulation of cell population proliferation • negative regulation of Notch signaling pathway • erythrocyte development • negative regulation of cellular senescence • regulation of apoptotic process • negative regulation of mitotic cell cycle DNA replication • positive regulation of regulatory T cell differentiation • cytokine-mediated signaling pathway |
---|
Джерела:Amigo / QuickGO | |
Шаблон експресії |
---|
|
Більше даних |
Ортологи |
---|
Види | Людина | Миша |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (мРНК) | | NM_001130845 NM_001134738 NM_001706 NM_138931 |
| |
---|
RefSeq (білок) | | NP_001124317 NP_001128210 NP_001697 |
| |
---|
Локус (UCSC) | Хр. 3: 187.72 – 187.75 Mb | Хр. 16: 23.78 – 23.81 Mb |
---|
PubMed search | [1] | [2] |
---|
Вікідані |
Див./Ред. для людей | Див./Ред. для мишей |
|