Protein-coding gene in the species Homo sapiens
| KCNJ13 |
|---|
|
| Identifiers |
|---|
| Aliases | KCNJ13, KIR1.4, KIR7.1, LCA16, SVD, potassium voltage-gated channel subfamily J member 13, potassium inwardly rectifying channel subfamily J member 13 |
|---|
| External IDs | OMIM: 603208 MGI: 3781032 HomoloGene: 55638 GeneCards: KCNJ13 |
|---|
| Gene location (Human) |
|---|
 | | Chr. | Chromosome 2 (human)[1] |
|---|
| | Band | 2q37.1 | Start | 232,765,802 bp[1] |
|---|
| End | 232,776,565 bp[1] |
|---|
|
| Gene location (Mouse) |
|---|
 | | Chr. | Chromosome 1 (mouse)[2] |
|---|
| | Band | 1 D|1 | Start | 87,314,085 bp[2] |
|---|
| End | 87,322,451 bp[2] |
|---|
|
| RNA expression pattern |
|---|
| Bgee | | Human | Mouse (ortholog) |
|---|
| Top expressed in | - retinal pigment epithelium
- jejunal mucosa
- sural nerve
- Achilles tendon
- duodenum
- bone marrow cells
- corpus callosum
- sperm
- seminal vesicula
- kidney
|
| | Top expressed in | - retinal pigment epithelium
- iris
- otolith organ
- utricle
- ciliary body
- sciatic nerve
- olfactory epithelium
- stria vascularis
- right lung lobe
- left lung lobe
|
| | More reference expression data |
|
|---|
| BioGPS | 
 | | More reference expression data |
|
|---|
|
| Gene ontology |
|---|
| Molecular function | - inward rectifier potassium channel activity
- voltage-gated ion channel activity
| | Cellular component | - integral component of membrane
- integral component of plasma membrane
- membrane
| | Biological process | - potassium ion transport
- regulation of ion transmembrane transport
- ion transport
- potassium ion import across plasma membrane
| | Sources:Amigo / QuickGO |
|
| Orthologs |
|---|
| Species | Human | Mouse |
|---|
| Entrez | | |
|---|
| Ensembl | | |
|---|
| UniProt | | |
|---|
| RefSeq (mRNA) | |
|---|
NM_002242
NM_001172416
NM_001172417 |
| |
|---|
| RefSeq (protein) | |
|---|
NP_001165887
NP_001165888
NP_002233 |
| |
|---|
| Location (UCSC) | Chr 2: 232.77 – 232.78 Mb | Chr 1: 87.31 – 87.32 Mb |
|---|
| PubMed search | [3] | [4] |
|---|
|
| Wikidata |
| View/Edit Human | View/Edit Mouse |
|
Potassium inwardly-rectifying channel, subfamily J, member 13 (KCNJ13) is a human gene encoding the Kir7.1 protein.[5]
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000115474 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000079436 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: KCNJ13 potassium inwardly-rectifying channel, subfamily J, member 13".
Further reading
- Kubo Y, Adelman JP, Clapham DE, Jan LY, Karschin A, Kurachi Y, Lazdunski M, Nichols CG, Seino S, Vandenberg CA (December 2005). "International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels". Pharmacological Reviews. 57 (4): 509–26. doi:10.1124/pr.57.4.11. PMID 16382105. S2CID 11588492.
- Krapivinsky G, Medina I, Eng L, Krapivinsky L, Yang Y, Clapham DE (May 1998). "A novel inward rectifier K+ channel with unique pore properties". Neuron. 20 (5): 995–1005. doi:10.1016/S0896-6273(00)80480-8. PMID 9620703. S2CID 16356235.
- Partiseti M, Collura V, Agnel M, Culouscou JM, Graham D (August 1998). "Cloning and characterization of a novel human inwardly rectifying potassium channel predominantly expressed in small intestine". FEBS Letters. 434 (1–2): 171–6. doi:10.1016/S0014-5793(98)00972-7. PMID 9738472. S2CID 27138272.
- Döring F, Derst C, Wischmeyer E, Karschin C, Schneggenburger R, Daut J, Karschin A (November 1998). "The epithelial inward rectifier channel Kir7.1 displays unusual K+ permeation properties". The Journal of Neuroscience. 18 (21): 8625–36. doi:10.1523/JNEUROSCI.18-21-08625.1998. PMC 6793533. PMID 9786970.
- Derst C, Döring F, Preisig-Müller R, Daut J, Karschin A, Jeck N, Weber S, Engel H, Grzeschik KH (December 1998). "Partial gene structure and assignment to chromosome 2q37 of the human inwardly rectifying K+ channel (Kir7.1) gene (KCNJ13)". Genomics. 54 (3): 560–3. doi:10.1006/geno.1998.5598. PMID 9878260.
- Nakamura N, Suzuki Y, Sakuta H, Ookata K, Kawahara K, Hirose S (September 1999). "Inwardly rectifying K+ channel Kir7.1 is highly expressed in thyroid follicular cells, intestinal epithelial cells and choroid plexus epithelial cells: implication for a functional coupling with Na+,K+-ATPase". The Biochemical Journal. 342 ( Pt 2) (2): 329–36. doi:10.1042/0264-6021:3420329. PMC 1220469. PMID 10455019.
- Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (January 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
